SCHEMBL10108557

SCHEMBL10108557

Cc1cccc(-n2c3ccc(-c4ccc5c(c4)c4cc(-c6ccc7c(c6)c6cc(C)ccc6n7-c6cccc(C(F)(F)F)c6)ccc4n5-c4ccc(-c5c6ccccc6c(-c6ccccc6)c6ccccc56)cc4)cc3c3cc(C(F)(F)F)ccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.39
PPARA Q07869 2/20 0.39
ICMT O60725 1/20 0.37
NOTUM Q6P988 1/20 0.36
MAPT P10636 2/20 0.36
CYP1A2 P05177 2/20 0.36
NPC1 O15118 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
RAB9A P51151 1/20 0.36
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
KIF11 P52732 1/20 0.35
MTOR P42345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10108386 0.94 PPARG (0.40) PPARGPPARAICMTNOTUMMAPT
SCHEMBL10108542 0.94 PPARG (0.40) PPARGPPARAICMTNOTUMMAPT
SCHEMBL14092849 0.92 KIF11 (0.39) PPARGPPARAICMTMAPTMGAM
SCHEMBL10108767 0.92 DHODH (0.39) PPARGPPARAICMTMGAMGAA
SCHEMBL262409 0.92 PPARG (0.42) PPARGPPARAMAPTNPC1RAB9A
SCHEMBL10108552 0.91 KIF11 (0.39) PPARGPPARAICMTMAPTMGAM
SCHEMBL10108736 0.90 KIF11 (0.40) PPARGPPARAMAPTMGAMGAA
SCHEMBL262709 0.90 PPARG (0.43) PPARGPPARANPC1RAB9AMGAM
SCHEMBL262401 0.88 GAA (0.40) PPARGICMTNOTUMMAPTRAB9A
SCHEMBL12853006 0.87 PPARG (0.39) PPARGPPARAMAPTMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9136479-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20150004731-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2015-01-01 US disclosed
US-8816098-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-26 US disclosed
US-8530672-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 US disclosed
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-12-06 US disclosed
US-8278655-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-02 US disclosed
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A PPARG 1293/4885PPARA 2260/4885ICMT 1476/4885
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A PPARG 1293/4885PPARA 2260/4885ICMT 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.