SCHEMBL1010914

SCHEMBL1010914

CCCCCCCCCCCCCCCCCCC1=C2CCC(C1)C2

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.37
SPHK1 Q9NYA1 7/20 0.35
NR5A2 O00482 5/20 0.33
CYP1A2 P05177 2/20 0.32
NR5A1 Q13285 5/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SPHK2 Q9NRA0 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11181371 1.00 SCD (0.37) SCDSPHK1NR5A2CYP1A2NR5A1
SCHEMBL9122406 1.00 SCD (0.37) SCDSPHK1NR5A2CYP1A2NR5A1
SCHEMBL1012468 1.00 SCD (0.37) SCDSPHK1NR5A2CYP1A2NR5A1
SCHEMBL679390 1.00 SCD (0.37) SCDSPHK1NR5A2CYP1A2NR5A1
SCHEMBL1011861 1.00 SCD (0.37) SCDSPHK1NR5A2CYP1A2NR5A1
SCHEMBL797511 0.98 SCD (0.34) SCDSPHK1NR5A2MEN1KMT2A
SCHEMBL239983 0.92
Ammonia Solution, Strong SCHEMBL21411456 0.82
SCHEMBL2961195 0.74 SCD (0.45) SCDNR5A2
SCHEMBL9340336 0.70 SCD (0.50) SCDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP claimed
US-6838489-B2 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor CYMETECH, LLC (US) 2005-01-04 US claimed
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-07-31 US claimed
EP-1423195-B1 HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2016-03-02 EP disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP disclosed
CN-1911942-B Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts CALIFORNIA INST OF TECHN 2010-06-23 CN disclosed
CN-1911942-A Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts CALIFORNIA INST OF TECHN (US) 2007-02-14 CN disclosed
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US disclosed
EP-1423195-A4 HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2005-06-29 EP disclosed
CN-1208360-C In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO (JP) 2005-06-29 CN disclosed
US-20030069374-A1 Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY AND CYMETECH, LLP 2003-04-10 US disclosed
US-6538087-B2 (hetero)polycyclic polymer PROMERUS, LLC 2003-03-25 US disclosed
WO-2003011455-A1 HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-02-13 WO disclosed
US-20020103317-A1 Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same SUMITOMO BAKELITE CO., LTD. (JP) 2002-08-01 US disclosed
US-20020064896-A1 Optical waveguides and methods for making the same 3M INNOVATIVE PROPERTIES COMPANY 2002-05-30 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
WO-2002010231-A2 POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME GOODRICH CORPORATION (US) 2002-02-07 WO disclosed
WO-2002010810-A2 OPTICAL WAVEGUIDES AND METHODS FOR MAKING THE SAME GOODRICH CORPORATION (US) 2002-02-07 WO disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069374-A1 Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts CLIC1, CBR1, KAT5 SCD 3439/4885SPHK1 299/4885NR5A2 1013/4885
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 SCD 210/4885SPHK1 3568/4885NR5A2 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.