Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901390 | 0.85 | TDP1 (0.70) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos Methyl SCHEMBL29358873 | 0.81 | TDP1 (0.77) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos Methyl SCHEMBL26456 | 0.81 | TDP1 (0.77) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos Methyl SCHEMBL7876104 | 0.81 | TDP1 (0.77) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos-Ethyl SCHEMBL29413995 | 0.80 | TDP1 (1.00) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos-Ethyl SCHEMBL7869678 | 0.80 | TDP1 (1.00) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos-Ethyl SCHEMBL74180 | 0.80 | TDP1 (1.00) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| Pirimiphos Methyl SCHEMBL21357930 | 0.79 | TDP1 (0.68) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| SCHEMBL11355114 | 0.78 | TDP1 (0.60) | TDP1CYP3A4TSHRALDH1A1TP53 | |
| SCHEMBL11374668 | 0.78 | TDP1 (0.60) | TDP1CYP3A4TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846567-B2 | Active compound combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | ACHE, DDT, BCHE | TDP1 2269/4885CYP3A4 279/4885TSHR 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.