Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26227708 | 0.81 | ESR1 (0.42) | ESR1ESR2ABCB1CHRNB4CHRNA3 | |
| SCHEMBL18752234 | 0.81 | ESR1 (0.34) | ESR1ESR2ABCB1HTR2AHTR2C | |
| SCHEMBL17974163 | 0.79 | ESR1 (0.40) | ESR1ESR2ABCB1HTR2AHTR2C | |
| SCHEMBL21140148 | 0.78 | ESR1 (0.37) | ESR1ESR2HTR2AHTR2CHRH1 | |
| SCHEMBL10109660 | 0.76 | — | — | |
| SCHEMBL10109653 | 0.75 | LMNA (0.42) | ESR1ESR2 | |
| SCHEMBL9391610 | 0.74 | ESR1 (0.47) | ESR1ESR2ABCB1CHRNB4CHRNA3 | |
| SCHEMBL10682685 | 0.74 | ESR1 (0.51) | ESR1ESR2ABCB1CHRNB4CHRNA3 | |
| SCHEMBL7317272 | 0.74 | ESR1 (0.47) | ESR1ESR2ABCB1CHRNB4CHRNA3 | |
| SCHEMBL30901243 | 0.71 | MAOA (0.39) | ESR1ESR2ABCB1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120074395-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2012-03-29 | — | — | US | disclosed |
| US-20120074395-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2012-03-29 | — | — | US | disclosed |