Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12257510 | 0.85 | RORC (0.45) | RORCPLGPLAUTUBB4ATUBB | |
| SCHEMBL6962451 | 0.82 | RORC (0.46) | RORCPLGPLAUTUBB4ATUBB | |
| SCHEMBL6962453 | 0.82 | RORC (0.46) | RORCPLGPLAUTUBB4ATUBB | |
| SCHEMBL19553339 | 0.81 | HTR2C (0.53) | PLGPLAUHTR2CHTR2A | |
| SCHEMBL16219087 | 0.81 | PLG (0.43) | PLGPLAUHTR2CHTR2A | |
| SCHEMBL24669590 | 0.79 | PLG (0.45) | PLGPLAUHTR2CHTR2A | |
| SCHEMBL31735936 | 0.79 | GLO1 (0.46) | PLGPLAUHTR2CHTR2AMTNR1A | |
| SCHEMBL218056 | 0.78 | PRKCI (0.58) | PLAUTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31265088 | 0.78 | PRKCI (0.58) | PLAUTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL110146 | 0.78 | PRKCI (0.58) | CYP19A1FAAHCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509518-B1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC (US) | 2012-02-08 | — | — | EP | disclosed |