Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17524524 | 0.92 | TAAR1 (0.48) | TAAR1ALDH1A1MAPTHPGDADRA2A | |
| SCHEMBL10109880 | 0.92 | TAAR1 (0.48) | TAAR1ALDH1A1MAPTHPGDADRA2A | |
| SCHEMBL4400993 | 0.83 | ADRA2A (0.52) | TAAR1ALDH1A1MAPTADRA2AADRA2B | |
| SCHEMBL18323114 | 0.83 | ADRA2A (0.52) | TAAR1ALDH1A1MAPTADRA2AADRA2B | |
| SCHEMBL6723846 | 0.79 | CHKA (0.49) | TAAR1ALDH1A1MEN1ESR1KMT2A | |
| SCHEMBL14065149 | 0.79 | PNPLA2 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6723962 | 0.79 | CHKA (0.49) | TAAR1ALDH1A1MEN1ESR1KMT2A | |
| SCHEMBL6723803 | 0.79 | CHKA (0.49) | TAAR1ALDH1A1MEN1ESR1KMT2A | |
| SCHEMBL4058687 | 0.79 | MEN1 (0.48) | TAAR1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL12424022 | 0.79 | MEN1 (0.48) | TAAR1ALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9087997-B2 | Aromatic amine derivative and organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2015-07-21 | — | — | US | disclosed |
| US-8703304-B2 | Aromatic amine derivative and organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2014-04-22 | — | — | US | disclosed |
| US-20140061630-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2014-03-06 | — | — | US | disclosed |
| US-20120161119-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20100001636-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120161119-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE | TYR, TERF2, SAT1 | TAAR1 231/4885ALDH1A1 452/4885MAPT 202/4885 |
| US-20100001636-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE | TYR, TERF2, SAT1 | TAAR1 299/4885ALDH1A1 432/4885MAPT 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.