SCHEMBL10109944

SCHEMBL10109944

CC1(C)c2cc(-c3cccc4c3oc3ccccc34)ccc2-c2ccc(N(c3ccc(-c4cccc(-c5ccccc5)c4)cc3)c3ccc(-c4ccccc4)c4ccccc34)cc21

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
GGPS1 O95749 1/20 0.35
PRKDC P78527 4/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916614 0.98 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL10109941 0.98 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL9916635 0.98 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL9916647 0.98 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL9916583 0.98 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL10307123 0.95 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL21858965 0.95 ALOX5 (0.38) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL9916554 0.94 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL18926256 0.93 ALOX5 (0.38) ALOX5GGPS1PRKDCPTGES2
SCHEMBL9916578 0.93 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 US disclosed
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 US disclosed
US-9024521-B2 Organic EL display device and method of manufacturing the same SONY CORPORATION (JP) 2015-05-05 US disclosed
US-9024521-B2 Organic EL display device and method of manufacturing the same SONY CORPORATION (JP) 2015-05-05 US disclosed
US-8823255-B2 Organic el display device and method of manufacturing the same SONY CORPORATION (JP) 2014-09-02 US disclosed
US-8823255-B2 Organic el display device and method of manufacturing the same SONY CORPORATION (JP) 2014-09-02 US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20120242218-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120242218-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE TYR, TERF2, SAT1 ALOX5 3505/4885GGPS1 2974/4885PRKDC 2266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.