SCHEMBL1011005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1949996	0.89	NPC1 (0.45)	ARMAOAMAOBSRCSMN1; SMN2
	SCHEMBL13864205	0.87	TLR4 (0.42)	ARMAOAMAOBSRCSMN1; SMN2
	SCHEMBL1011104	0.85	SMN1; SMN2 (0.55)	MAOAMAOBSRCSMN1; SMN2ALDH1A1
	SCHEMBL2174551	0.85	SMN1; SMN2 (0.55)	MAOAMAOBSRCSMN1; SMN2ALDH1A1
	SCHEMBL1008004	0.85	SRC (0.41)	ARMAOAMAOBSRCSMN1; SMN2
	SCHEMBL2552246	0.84	SRC (0.45)	MAOAMAOBSRCSMN1; SMN2ALDH1A1
	SCHEMBL29342586	0.84	L3MBTL1 (0.50)	MAOAMAOBSRCSMN1; SMN2ALDH1A1
	SCHEMBL767041	0.80	TDP1 (0.55)	ARSMN1; SMN2ALDH1A1TDP1NPC1
	SCHEMBL2902147	0.78	L3MBTL1 (0.49)	ARSMN1; SMN2ALDH1A1TDP1TSHR
	SCHEMBL8581214	0.78	POLB (0.50)	MAOAMAOBSRCSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.