Sugi Predict

Sugi Predict / Compounds / SCHEMBL10110484

SCHEMBL10110484

SCHEMBL10110484

CC1(C)c2cc(-c3ccc4c(c3)oc3ccccc34)ccc2-c2ccc(N(c3ccc(-c4ccccc4-c4ccccc4)cc3)c3ccc(-c4ccccc4-c4ccccc4)cc3)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP12 P39900 1/20 0.34
▸ MMP13 P45452 1/20 0.34
▸ AHR P35869 2/20 0.33
▸ PGR P06401 1/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ MAPT P10636 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ THRB P10828 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ BLM P54132 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ HCRTR1 O43613 1/20 0.32
▸ TNKS O95271 1/20 0.32
▸ MAOA P21397 2/20 0.32
▸ PDK2 Q15119 1/20 0.32
▸ ALK Q9UM73 3/20 0.32
▸ PRKDC P78527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916718 0.99 MMP12 (0.35) MMP12MMP13AHRPGRMEN1
SCHEMBL9916726 0.99 MMP12 (0.35) MMP12MMP13AHRPGRMEN1
SCHEMBL9916723 0.99 MMP12 (0.35) MMP12MMP13AHRPGRMEN1
SCHEMBL9916703 0.98 HCRTR1 (0.33) MMP12MMP13AHRPGRMEN1
SCHEMBL18697091 0.97 MMP12 (0.34) MMP12MMP13AHRPGRMEN1
SCHEMBL18697077 0.97 MMP12 (0.34) MMP12MMP13AHRPGRMEN1
SCHEMBL9916696 0.96 MMP12 (0.35) MMP12MMP13AHRPGRMEN1
SCHEMBL18926259 0.96 MMP12 (0.35) MMP12MMP13AHRPGRMEN1
SCHEMBL18926258 0.96 MMP12 (0.35) MMP12MMP13AHRPGRMEN1
SCHEMBL9916700 0.96 MMP12 (0.35) MMP12MMP13AHRPGRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 — — US disclosed
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 — — US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 — — US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 — — US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 — — US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 — — US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 — — US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE TYR, TERF2, SAT1 MMP12 4810/4885MMP13 4764/4885AHR 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.