Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 4/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448308 | 1.00 | TDP1 (0.44) | TDP1ABL1RIN1NR2E3PPARG | |
| SCHEMBL497854 | 0.75 | — | — | |
| SCHEMBL10110596 | 0.75 | — | — | |
| SCHEMBL14026498 | 0.73 | — | — | |
| SCHEMBL12663905 | 0.73 | — | — | |
| SCHEMBL20123222 | 0.70 | TDP1 (0.44) | TDP1ABL1RIN1NR2E3PPARG | |
| SCHEMBL3384844 | 0.69 | — | — | |
| SCHEMBL6036786 | 0.69 | — | — | |
| SCHEMBL6561453 | 0.65 | ABL1 (0.65) | TDP1ABL1RIN1NR2E3PPARG | |
| SCHEMBL6269532 | 0.63 | TDP1 (0.36) | TDP1ABL1RIN1NR2E3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033216-A1 | POLYMER CONJUGATES OF NESIRITIDE PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |