SCHEMBL10110682

SCHEMBL10110682

CCC(C)(C)C(=O)OCCNC(=O)C12CC3CC(CC(C(=O)O)(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ALDH1A1 P00352 1/20 0.41
EPHX2 P34913 1/20 0.41
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.36
PKM P14618 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123445 0.87 LMNA (0.43) LMNAALDH1A1EPHX2KDM4EHTT
SCHEMBL13219551 0.83 NPSR1 (0.51) LMNAALDH1A1HTTNPSR1PKM
SCHEMBL14802433 0.79 ALDH1A1 (0.38) LMNAALDH1A1NPSR1TSHRPKM
SCHEMBL16659670 0.76 PREP (0.43) LMNAALDH1A1EPHX2TSHRPKM
SCHEMBL14252316 0.76 LMNA (0.45) LMNAALDH1A1EPHX2KDM4EHTT
SCHEMBL12404703 0.74 ALDH1A1 (0.47) LMNAALDH1A1NPSR1PKML3MBTL1
SCHEMBL106316 0.74 ALDH1A1 (0.42) LMNAALDH1A1NPSR1PKML3MBTL1
SCHEMBL14802399 0.73 ALDH1A1 (0.37) LMNAALDH1A1NPSR1PKML3MBTL1
SCHEMBL13241926 0.72 ALDH1A1 (0.40) LMNAALDH1A1NPSR1PKML3MBTL1
SCHEMBL2618623 0.72 ALDH1A1 (0.46) LMNAALDH1A1NPSR1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7964334-B2 Mixture containing urea compound as photoinitiator; curing by exposure to laser light FUJIFILM CORPORATION (JP) 2011-06-21 US disclosed
US-7955781-B2 Negative-working photosensitive material and negative-working planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-7820357-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2010-10-26 US disclosed
US-7604923-B2 Image forming method FUJIFILM CORPORATION (JP) 2009-10-20 US disclosed
US-20090087780-A1 NEGATIVE-WORKING PHOTOSENSITIVE MATERIAL AND NEGATIVE-WORKING PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087788-A1 CURABLE COMPOSITION, IMAGE FORMING MATERIAL, AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090075206-A1 CURABLE COMPOSITION, IMAGE FORMING MATERIAL, AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
US-7445882-B2 Image recording material FUJIFILM CORPORTATION (JP) 2008-11-04 US disclosed
US-20080241744-A1 CURABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080057439-A1 Image recording material FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070298351-A1 IMAGE RECORDING MATERIAL, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-7291443-B2 Polymerizable composition and image-recording material using the same FUJIFILM CORPORATION (JP) 2007-11-06 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070148593-A1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION 2007-06-28 US disclosed