Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 3/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2194865 | 0.99 | LPO (0.55) | LPOCMA1SIGMAR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL2011318 | 0.99 | LPO (0.55) | LPOCMA1SIGMAR1LMNATP53 | |
| SCHEMBL1009269 | 0.81 | MAPT (0.46) | CMA1SIGMAR1LMNATP53MAPT | |
| Bromide SCHEMBL2196188 | 0.80 | MAPT (0.45) | CMA1SIGMAR1LMNAMAPTKDM4E | |
| SCHEMBL20138573 | 0.80 | CYP11B1 (0.53) | TP53MAPTKDM4EALDH1A1TAAR1 | |
| SCHEMBL27696269 | 0.79 | LPO (0.68) | LPOCMA1SIGMAR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL2012582 | 0.79 | CYP11B1 (0.55) | TP53MAPTKDM4EALDH1A1TAAR1 | |
| SCHEMBL1009623 | 0.78 | HSP90AA1 (0.49) | SIGMAR1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL667065 | 0.77 | PON1 (0.50) | CMA1SIGMAR1LMNATP53MAPT | |
| Bromide SCHEMBL2194611 | 0.77 | HSP90AA1 (0.48) | SIGMAR1LMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268652-A2 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009118475-A2 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-01 | — | — | WO | disclosed |