Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2011318

COc1cccc(Cn2cc[n+](C)c2)c1.[Cl-]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPO P22079 3/20 0.55
CMA1 P23946 1/20 0.50
SIGMAR1 Q99720 2/20 0.48
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
IDO1 P14902 2/20 0.43
AGXT P21549 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1011073 0.99 LPO (0.56) LPOCMA1SIGMAR1LMNATP53
Bromide SCHEMBL2194865 0.97 LPO (0.55) LPOCMA1SIGMAR1LMNATP53
Hydrochloric Acid SCHEMBL2012582 0.81 CYP11B1 (0.55) TP53MAPTKDM4EALDH1A1POLB
SCHEMBL1009269 0.80 MAPT (0.46) CMA1SIGMAR1LMNATP53MAPT
Bromide SCHEMBL2196188 0.79 MAPT (0.45) CMA1SIGMAR1LMNAMAPTKDM4E
SCHEMBL20138573 0.79 CYP11B1 (0.53) TP53MAPTKDM4EALDH1A1POLB
Hydrochloric Acid SCHEMBL383000 0.78 PON1 (0.52) CMA1SIGMAR1LMNATP53MAPT
SCHEMBL27696269 0.78 LPO (0.68) LPOCMA1SIGMAR1LMNATP53
SCHEMBL1009623 0.77 HSP90AA1 (0.49) SIGMAR1LMNAKDM4EALDH1A1POLB
SCHEMBL667065 0.76 PON1 (0.50) CMA1SIGMAR1LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2475677-B1 PROCESSES FOR PRODUCING SILK DOPE COMMW SCIENT IND RES ORG (AU) 2018-08-01 EP disclosed
US-20150259571-A1 LIGNIN MEMBRANES AND COATINGS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2015-09-17 US disclosed
US-8674077-B2 Processes for producing silk dope COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2014-03-18 US disclosed
CN-102812036-A Processes For Producing Silk Dope COMMW SCIENT IND RES ORGANISATION 2012-12-05 CN disclosed
US-20120302734-A1 Processes for Producing Silk Dope COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-11-29 US disclosed
US-8182557-B2 Pretreating lignocellulosic (woody biomass) by dissolving in ionic liquid comprising imidazolium or pyridinium salt to form a solution; precipitating with regenerating solvent (water); hydrolysis to form sugar and fermentation to form bioethanol; recycling through evaporation; environmentally friendly NORTH CAROLINA STATE UNIVERSITY (US) 2012-05-22 US disclosed
US-7959765-B2 Dissolving in liquid; pyrolysis NORTH CAROLINA STATE UNIVERSTIY (US) 2011-06-14 US disclosed
US-20080190013-A1 USE OF LIGNOCELLULOSICS SOLVATED IN IONIC LIQUIDS FOR PRODUCTION OF BIOFUELS NORTH CAROLINA STATE UNIVERSITY 2008-08-14 US disclosed
WO-2008098032-A2 USE OF LIGNOCELLULOSICS SOLVATED IN IONIC LIQUIDS FOR PRODUCTION OF BIOFUELS NORTH CAROLINA STATE UNIVERSITY (US) 2008-08-14 WO disclosed
WO-2008098036-A1 PRODUCT PREPARATION AND RECOVERY FROM THERMOLYSIS OF LIGNOCELLULOSICS IN IONIC LIQUIDS NORTH CAROLINA STATE UNIVERSITY (US) 2008-08-14 WO disclosed
WO-2008098037-A2 POLYMER DERIVATIVES AND COMPOSITES FROM THE DISSOLUTION OF LIGNOCELLULOSICS IN IONIC LIQUIDS NORTH CAROLINA STATE UNIVERSITY (US) 2008-08-14 WO disclosed
US-20080188636-A1 POLYMER DERIVATIVES AND COMPOSITES FROM THE DISSOLUTION OF LIGNOCELLULOSICS IN IONIC LIQUIDS NORTH CAROLINA STATE UNIVERSITY 2008-08-07 US disclosed
US-20080185112-A1 PRODUCT PREPARATION AND RECOVERY FROM THERMOLYSIS OF LIGNOCELLULOSICS IN IONIC LIQUIDS NORTH CAROLINA STATE UNIVERSITY 2008-08-07 US disclosed