SCHEMBL10110874

SCHEMBL10110874

CC(C)(C)C(=S)Nc1ccc(C2=C3C=CC(=O)C=C3OC3C=C(O)C=CC23)c(C(=O)O)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16602269 0.91 KDM4C (0.32) KDM4C
SCHEMBL18625282 0.89 KDM4C (0.35) KDM4C
SCHEMBL14367912 0.88 KDM4C (0.34) KDM4C
SCHEMBL15004023 0.82 KDM4C (0.37) KDM4C
SCHEMBL10110877 0.82 PTPN1 (0.31) —
SCHEMBL10063378 0.81 KDM4C (0.35) KDM4C
SCHEMBL14392241 0.80 KDM4E (0.36) —
SCHEMBL16522851 0.77 — —
SCHEMBL14999650 0.74 — —
SCHEMBL16093127 0.74 FKBP1A (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9333232-B2 Methods for treating papilloma virus infection NANOVIR LLC (US) 2016-05-10 — — US disclosed
US-9290551-B2 Compounds for treating papilloma virus infection NANOVIR LLC (US) 2016-03-22 — — US disclosed
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-08-27 — — US disclosed
US-8993609-B2 Compounds for treating papilloma virus infection NANOVIR, LLC (US) 2015-03-31 — — US disclosed
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION NANOVIR, LLC (US) 2012-09-06 — — US disclosed
US-8119677-B2 Polyamides containing amino butyric acid-based building blocks NANOVIR, LLC (US) 2012-02-21 — — US disclosed
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2010-01-21 — — US disclosed
US-20090306164-A1 Methods for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2009-12-10 — — US disclosed
US-7589171-B2 Polyamides for treating human papilloma virus NANOVIR, LLC (US) 2009-09-15 — — US disclosed
US-20070293417-A1 Polyamides for treating human papilloma virus NANOVIR, LLC 2007-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 KDM4C 1479/4885
US-20090306164-A1 Methods for Treating Papilloma Virus Infection POLI, VHL, TLR3 KDM4C 1286/4885
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 KDM4C 1479/4885
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection POLI, PMAIP1, TLR3 KDM4C 1211/4885
US-20070293417-A1 Polyamides for treating human papilloma virus POLI, PARG, PARN KDM4C 1997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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