SCHEMBL10110877

SCHEMBL10110877

CC(=O)c1ccc(C2=C3C=CC(=O)C=C3OC3C=C(O)C=CC23)c(C(=O)O)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 1/20 0.31
▸ AKR1C3 P42330 1/20 0.30
▸ AKR1C2 P52895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14392242 1.00 PTPN1 (0.31) PTPN1AKR1C3AKR1C2
SCHEMBL16602269 0.86 KDM4C (0.32) —
SCHEMBL14392241 0.86 KDM4E (0.36) PTPN1
SCHEMBL10125912 0.86 — —
SCHEMBL14367912 0.82 KDM4C (0.34) —
SCHEMBL10110874 0.82 KDM4C (0.31) —
SCHEMBL12518496 0.80 KDM4C (0.40) —
SCHEMBL15004023 0.77 KDM4C (0.37) —
SCHEMBL20647844 0.63 — —
SCHEMBL458033 0.59 CSNK2A1 (0.59) PTPN1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9333232-B2 Methods for treating papilloma virus infection NANOVIR LLC (US) 2016-05-10 — — US disclosed
US-9333232-B2 Methods for treating papilloma virus infection NANOVIR LLC (US) 2016-05-10 — — US disclosed
US-9290551-B2 Compounds for treating papilloma virus infection NANOVIR LLC (US) 2016-03-22 — — US disclosed
US-9290551-B2 Compounds for treating papilloma virus infection NANOVIR LLC (US) 2016-03-22 — — US disclosed
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-08-27 — — US disclosed
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-08-27 — — US disclosed
US-8993609-B2 Compounds for treating papilloma virus infection NANOVIR, LLC (US) 2015-03-31 — — US disclosed
US-8993609-B2 Compounds for treating papilloma virus infection NANOVIR, LLC (US) 2015-03-31 — — US disclosed
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION NANOVIR, LLC (US) 2012-09-06 — — US disclosed
US-8119677-B2 Polyamides containing amino butyric acid-based building blocks NANOVIR, LLC (US) 2012-02-21 — — US disclosed
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2010-01-21 — — US disclosed
US-20090306164-A1 Methods for Treating Papilloma Virus Infection NANOVIR, LLC (US) 2009-12-10 — — US disclosed
US-7589171-B2 Polyamides for treating human papilloma virus NANOVIR, LLC (US) 2009-09-15 — — US disclosed
US-20070293417-A1 Polyamides for treating human papilloma virus NANOVIR, LLC 2007-12-20 — — US disclosed
US-20070293417-A1 Polyamides for treating human papilloma virus NANOVIR, LLC 2007-12-20 — — US disclosed
WO-2007103584-A2 POLYAMIDES FOR TREATING HUMAN PAPILLOMA VIRUS NANOVIR, LLC (US) 2007-09-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225809-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 PTPN1 3030/4885AKR1C3 1605/4885AKR1C2 2591/4885
US-20090306164-A1 Methods for Treating Papilloma Virus Infection POLI, VHL, TLR3 PTPN1 2404/4885AKR1C3 2245/4885AKR1C2 3166/4885
US-20150239943-A1 COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION POLI, TLR3, PMAIP1 PTPN1 3030/4885AKR1C3 1605/4885AKR1C2 2591/4885
US-20100015084-A1 Compounds for Treating Papilloma Virus Infection POLI, PMAIP1, TLR3 PTPN1 3170/4885AKR1C3 2187/4885AKR1C2 3046/4885
US-20070293417-A1 Polyamides for treating human papilloma virus POLI, PARG, PARN PTPN1 3669/4885AKR1C3 4062/4885AKR1C2 4203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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