SCHEMBL458033

SCHEMBL458033

CC(=O)c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.59
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
PTGS2 P35354 2/20 0.57
CA12 O43570 1/20 0.57
ALOX5 P09917 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
AKR1C3 P42330 7/20 0.54
AKR1C2 P52895 7/20 0.54
MEN1 O00255 2/20 0.53
KDR P35968 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
TNF P01375 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSPD1 P10809 1/20 0.53
THRB P10828 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955411 1.00 CSNK2A1 (0.59) CSNK2A1CA1CA2PTGS2CA12
SCHEMBL7295677 0.87 PKM (0.57) AKR1C3AKR1C2PKMHTT
SCHEMBL8123713 0.85 RXRA (0.53) CA1CA2PTGS2CA12CA7
SCHEMBL330378 0.85 KDM4E (0.67) CSNK2A1CA1CA2PTGS2CA12
SCHEMBL30268239 0.85 KDM4E (0.67) CSNK2A1CA1CA2PTGS2CA12
SCHEMBL3183624 0.84 PKM (0.50) CSNK2A1CA1CA2PTGS2CA12
SCHEMBL3839830 0.83 ALDH1A1 (0.57) CA1CA2PTGS2CA12CA7
SCHEMBL29956901 0.83 KDM4E (0.59) CSNK2A1CA1CA2PTGS2CA12
SCHEMBL1162134 0.83 KDM4E (0.59) CSNK2A1CA1CA2PTGS2CA12
SCHEMBL7823608 0.83 CDC25A (0.59) AKR1C3AKR1C2KDM4EHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119924314-A Neutral peroxyacetic acid disinfectant for endoscope disinfection 山东新华医疗器械股份有限公司 2025-05-06 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-109678707-A A kind of deuterium-labeled D3The synthetic method of salbutamol 东莞暨南大学研究院 2019-04-26 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
EP-1429768-B1 NOVEL MEDICAMENTS FOR INHALATION BOEHRINGER INGELHEIM PHARMA (DE) 2016-11-16 EP claimed
US-20130315998-A1 Topical Foam Composition CIPLA LIMITED (IN) 2013-11-28 US claimed
US-20130202654-A1 Topical Foam Composition CIPLA LIMITED (IN) 2013-08-08 US claimed
EP-2503989-A2 TOPICAL FOAM COMPOSITION Cipla Limited (IN) 2012-10-03 EP claimed
EP-2503988-A2 TOPICAL FOAM COMPOSITION Cipla Limited (IN) 2012-10-03 EP claimed
WO-2011061516-A2 TOPICAL FOAM COMPOSITION CIPLA LIMITED (IN) 2011-05-26 WO claimed
US-20030180250-A1 Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2003-09-25 US claimed
US-20030130300-A1 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 US claimed
WO-2003024452-A1 NOVEL MEDICAMENTS FOR INHALATION BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2003-03-27 WO claimed
EP-1131058-A1 LOCAL DELIVERY OF DRUGS TO THE COLON FOR LOCAL TREATMENT OF COLONIC DISEASES Dexxon Ltd. (IL) 2001-09-12 EP claimed
US-6231888-B1 DRUG DELIVERY FOR DRUGS WITH CORES AND COATINGS PERIO PRODUCTS LTD. (IL) 2001-05-15 US claimed
EP-0763010-B1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR INC (US) 2000-08-30 EP claimed
WO-2000028974-A1 LOCAL DELIVERY OF DRUGS TO THE COLON FOR LOCAL TREATMENT OF COLONIC DISEASES DEXXON LTD. (IL) 2000-05-25 WO claimed
WO-1994014750-A1 NOVEL SALICYLIC ACID DERIVATIVES, THEIR SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME Richter Gedeon Vegyészeti Gyár Rt. (HU) 1994-07-07 WO claimed
EP-0383406-A1 A process for encapsulating an active ingredient UNILEVER N.V. (NL) 1990-08-22 EP claimed
US-4118401-A Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor AMERICAN HOECHST CORPORATION (US) 1978-10-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180250-A1 Compositions and complexes containing a macromolecular compound as potential anti-inflammatory agents CD68, MPO, MIF CSNK2A1 1448/4885CA1 3502/4885CA2 4055/4885
US-20130202654-A1 Topical Foam Composition LPXN, RFTN1, RDX CSNK2A1 1838/4885CA1 4651/4885CA2 4710/4885
US-20030130300-A1 Respiratory system disorders; synergistic mixtures ADRB3, ADRB1, CHRM3 CSNK2A1 1450/4885CA1 2913/4885CA2 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.