Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 19/20 | 1.00 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.67 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966094 | 1.00 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL5965946 | 1.00 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL6602263 | 0.97 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL13550161 | 0.97 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL15070993 | 0.97 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL14922432 | 0.93 | FKBP1A (0.86) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL8588531 | 0.93 | FKBP1A (0.86) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL8403621 | 0.93 | FKBP1A (0.86) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL10111026 | 0.93 | FKBP1A (0.86) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL25083114 | 0.92 | FKBP1A (0.84) | FKBP1AFKBP5FKBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106191-B2 | Compounds based on N- acyl-pipecolyl and N-acyl-prolyl ligand moieties for multimerizing chimeric proteins containing immunophilin-derived domains | ARIAD PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |