Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 1.00 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.65 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550161 | 1.00 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL15070993 | 1.00 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL5966094 | 0.97 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL5965946 | 0.97 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL10111024 | 0.97 | FKBP1A (1.00) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL14922432 | 0.90 | FKBP1A (0.86) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL8403621 | 0.90 | FKBP1A (0.86) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL8588531 | 0.90 | FKBP1A (0.86) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL10111026 | 0.90 | FKBP1A (0.86) | FKBP1AFKBP4FKBP5 | |
| SCHEMBL25083114 | 0.89 | FKBP1A (0.84) | FKBP1AFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218343-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GLIAMED, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-7960570-B2 | Small molecule inhibitors of rotamase enzyme activity | GLIAMED, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20100145071-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GLIAMED, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-7652060-B2 | Neurotrophic N-glyoxyl-prolyl ester compounds e.g. 3-phenyl-1-propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-pyrrolidinecarboxylate; non-immunosuppressive; side effect reduction; neurodegenerative diseases | Glia Med, Inc (US) | 2010-01-26 | — | — | US | disclosed |
| US-20080076817-A1 | Small Molecule Rotamase Enzyme Inhibitors | HAMILTON GREGORY S | 2008-03-27 | — | — | US | disclosed |
| EP-0992492-B1 | Small molecule inhibitors of rotamase enzyme activity | GUILFORD PHARM INC (US) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145071-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | FKBP8, FKBP1A, FKBP2 | FKBP1A 2/4885FKBP4 8/4885FKBP5 7/4885 |
| US-20110218343-A1 | SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY | FKBP8, FKBP1A, FKBP2 | FKBP1A 2/4885FKBP4 8/4885FKBP5 7/4885 |
| US-20080076817-A1 | Small Molecule Rotamase Enzyme Inhibitors | FKBP8, FKBP1A, FKBP2 | FKBP1A 2/4885FKBP4 8/4885FKBP5 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.