SCHEMBL10111285

SCHEMBL10111285

Cc1ccc(C(=Cc2ccc(N(c3ccccc3)c3ccc(C=C(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.57
ESR1 P03372 2/20 0.49
TRPM8 Q7Z2W7 2/20 0.46
ESR2 Q92731 1/20 0.44
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
CYP19A1 P11511 1/20 0.43
CYP11B2 P19099 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14199460 1.00 PTGS2 (0.57) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL5888390 0.98 PTGS2 (0.60) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL7733951 0.98 PTGS2 (0.60) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL18745204 0.98 PTGS2 (0.60) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL9887485 0.98 PTGS2 (0.60) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL13899091 0.98 PTGS2 (0.60) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL12009443 0.97 PTGS2 (0.57) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL12763721 0.97 PTGS2 (0.61) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL14570428 0.97 PTGS2 (0.61) PTGS2ESR1TRPM8ESR2MAPT
SCHEMBL5937761 0.97 PTGS2 (0.61) PTGS2ESR1TRPM8ESR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10635008-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-28 US disclosed
US-20190235400-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-08-01 US disclosed
US-20190235399-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-08-01 US disclosed
US-8097393-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-8097393-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-20070231733-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-20070231733-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed