SCHEMBL7733951

SCHEMBL7733951

Cc1ccc(C=C(c2ccccc2)c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.60
ESR1 P03372 2/20 0.47
CYP19A1 P11511 1/20 0.46
CYP11B2 P19099 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.45
CYP2D6 P10635 1/20 0.43
ESR2 Q92731 1/20 0.43
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9887485 1.00 PTGS2 (0.60) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL18745204 1.00 PTGS2 (0.60) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL13899091 1.00 PTGS2 (0.60) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL5888390 1.00 PTGS2 (0.60) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL12009443 0.98 PTGS2 (0.57) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL10111285 0.98 PTGS2 (0.57) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL14570428 0.98 PTGS2 (0.61) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL5937761 0.98 PTGS2 (0.61) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL14526458 0.98 PTGS2 (0.61) PTGS2ESR1CYP19A1CYP11B2TRPM8
SCHEMBL12763721 0.98 PTGS2 (0.61) PTGS2ESR1CYP19A1CYP11B2TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8551678-B2 Electrophotographic photoreceptor, image forming method, image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-10-08 US disclosed
US-6406825-B1 MULTILAYER; SUPPORT, PHOTOSENSITIVE LAYER AND THREE-DIMENSIONAL CROSSLINKED POLYMER KONICA CORPORATION (JP) 2002-06-18 US disclosed