Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660687 | 0.83 | TDP1 (0.41) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL101511 | 0.83 | TDP1 (0.41) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL21552111 | 0.80 | NPSR1 (0.36) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL10031420 | 0.80 | MEN1 (0.35) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL10126936 | 0.77 | EHMT2 (0.42) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL4358306 | 0.76 | HSD17B10 (0.36) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL9371847 | 0.74 | MAPT (0.47) | TDP1SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL12153325 | 0.74 | GAA (0.33) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL5695447 | 0.74 | TDP1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL5274068 | 0.74 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180088123-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2018-03-29 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2011096643-A1 | PHOTOCHROMIC MATERIAL | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | TDP1 2918/4885RAB9A 1851/4885CASP3 875/4885 |
| US-20180088123-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES | ALB, EPCAM, ELAVL1 | TDP1 4188/4885RAB9A 333/4885CASP3 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.