Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660687 | 1.00 | TDP1 (0.41) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL5695447 | 0.89 | TDP1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL5850640 | 0.85 | MEN1 (0.37) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL10111633 | 0.83 | TDP1 (0.41) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL31142510 | 0.80 | MEN1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL317019 | 0.80 | MEN1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL3418732 | 0.80 | MEN1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL665154 | 0.80 | MEN1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL10035871 | 0.80 | MEN1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 | |
| SCHEMBL661200 | 0.80 | MEN1 (0.39) | TDP1RAB9ACASP3ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126048-A | Preparation and application methods of cuporphyrin cyanine nano particles with switchable photodynamic and photothermal effects and chemical dynamic effects | 北京化工大学 | 2024-06-04 | — | — | CN | claimed |
| CN-118126048-A | Preparation and application methods of cuporphyrin cyanine nano particles with switchable photodynamic and photothermal effects and chemical dynamic effects | 北京化工大学 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024023138-A2 | CA-IX TARGETING FLUORESCENT PROBES | BRACCO IMAGING SPA (IT) | 2024-02-01 | — | — | WO | disclosed |
| CN-117447636-A | Photo/mechanochromatic material and preparation method and application thereof | 中国科学技术大学 | 2024-01-26 | — | — | CN | disclosed |
| US-20230382857-A1 | HEPTAMETHINE CYANINES FOR USE AS FLUORESCENT MARKERS OF THE BILIARY AND RENAL SYSTEMS | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2023-11-30 | — | — | US | disclosed |
| US-11787764-B2 | Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2023-10-17 | — | — | US | disclosed |
| US-11746086-B2 | Non-aggregating heptamethine cyanine fluorophores for in vivo imaging | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-05 | — | — | US | disclosed |
| US-11707537-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-07-25 | — | — | US | disclosed |
| WO-2023011656-A1 | FLUORESCENT DYE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 纳莹(上海)生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-20220267330-A1 | NEAR-INFRARED FLUORESCENT MOLECULE ACTIVE TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREOF | NANJING NUOYUAN MEDICAL DEVICES CO., LTD (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-0446731-A2 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0023671-B1 | PROCESS FOR THE PREPARATION OF CATIONIC DYESTUFFS | BAYER AG (DE) | 1982-02-03 | — | — | EP | disclosed |
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4281112-A | Process for the preparation of cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |
| EP-0023671-A1 | Process for the preparation of cationic dyestuffs | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4139274-A | Apparatus for changing color | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4110070-A | QUATERNIZING INDOLENINE METHINE COMPOUND ON FIBERS TO FORM CATIONIC DYE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1978-08-29 | — | — | US | disclosed |
| US-4007172-A | STYRYL DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787764-B2 | Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems | CD68, PAX2, PYGL | TDP1 3767/4885RAB9A 2403/4885CASP3 1244/4885 |
| US-11746086-B2 | Non-aggregating heptamethine cyanine fluorophores for in vivo imaging | CNDP2, MSN, CHAT | TDP1 1473/4885RAB9A 1172/4885CASP3 390/4885 |
| US-20230382857-A1 | HEPTAMETHINE CYANINES FOR USE AS FLUORESCENT MARKERS OF THE BILIARY AND RENAL SYSTEMS | CD68, HCCS, NR1H4 | TDP1 3471/4885RAB9A 2334/4885CASP3 1215/4885 |
| US-20220267330-A1 | NEAR-INFRARED FLUORESCENT MOLECULE ACTIVE TARGETING FOLATE RECEPTOR AND PREPARATION METHOD THEREOF | FOLR1, FOLR2, DHFR | TDP1 2842/4885RAB9A 539/4885CASP3 1026/4885 |
| US-11707537-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | IK, FAR1, SPR | TDP1 1492/4885RAB9A 782/4885CASP3 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.