SCHEMBL1011305

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30878610	1.00	HSD11B1 (0.54)	HSD11B1MAOATSHRCYP2D6HSD17B10
	SCHEMBL24029272	0.83	HSD11B1 (0.46)	HSD11B1MAOATSHRCYP2D6ADRA2A
	SCHEMBL1011098	0.82	MAOA (0.51)	MAOATSHRCYP2D6HSD17B10ALDH1A1
	SCHEMBL28295410	0.82	HSD11B1 (0.52)	HSD11B1TSHRCYP2D6ADRA2AADRA1A
	SCHEMBL26668035	0.81	MAOA (0.50)	HSD11B1MAOATSHRCYP2D6HSD17B10
	SCHEMBL17583889	0.81	MAOA (0.50)	MAOATSHRCYP2D6HSD17B10ALDH1A1
	SCHEMBL30471743	0.81	MAOA (0.50)	HSD11B1MAOATSHRCYP2D6HSD17B10
	SCHEMBL10518205	0.78	HSD11B1 (0.52)	HSD11B1TSHRADRA2AADRA1AADRA1D
	SCHEMBL1010830	0.77	PARP1 (0.42)	MAOATSHRHSD17B10ALDH1A1ADRA2A
	SCHEMBL9529706	0.76	HSD11B1 (0.47)	HSD11B1TSHRCYP2D6ADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.