Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416813 | 0.80 | KAT2B (1.00) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL10113238 | 0.80 | KAT2B (1.00) | KAT2BMAPTPOLBPKMPRSS1 | |
| Hydrochloric Acid SCHEMBL513245 | 0.79 | KAT2B (1.00) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL10622798 | 0.78 | KAT2B (0.72) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL14756010 | 0.78 | KAT2B (0.70) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL15984907 | 0.77 | KAT2B (0.97) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL2467761 | 0.76 | KAT2B (0.69) | KAT2BMAPTPOLBPKMPRSS1 | |
| Hydrochloric Acid SCHEMBL513299 | 0.76 | KAT2B (1.00) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL15984903 | 0.75 | KAT2B (0.79) | KAT2BMAPTPOLBPKMPRSS1 | |
| SCHEMBL2228520 | 0.74 | KAT2B (0.66) | KAT2BMAPTPOLBPKMPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028912-A1 | Methods of modulating bromodomains | J.David Gladstone Institute | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028912-A1 | Methods of modulating bromodomains | BAZ2A, BRPF3, BRD3 | KAT2B 37/4885MAPT 1884/4885POLB 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.