SCHEMBL2467761

SCHEMBL2467761

CN(C)c1ccc(NCCCN)c([N+](=O)[O-])c1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 9/20 0.69
MAPT P10636 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
POLB P06746 1/20 0.51
PKM P14618 1/20 0.51
PRSS1 P07477 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2472960 0.92 MAPT (0.58) KAT2BMAPTNPSR1SMN1; SMN2ALDH1A1
SCHEMBL10113238 0.82 KAT2B (1.00) KAT2BMAPTSMN1; SMN2ALDH1A1POLB
SCHEMBL29416813 0.82 KAT2B (1.00) KAT2BMAPTSMN1; SMN2ALDH1A1POLB
Hydrochloric Acid SCHEMBL513245 0.81 KAT2B (1.00) KAT2BMAPTSMN1; SMN2ALDH1A1POLB
SCHEMBL2474073 0.81 KAT2B (0.56) KAT2BMAPTNPSR1SMN1; SMN2ALDH1A1
SCHEMBL10622798 0.80 KAT2B (0.72) KAT2BMAPTALDH1A1POLBPKM
SCHEMBL8111762 0.80 MAPT (0.58) KAT2BMAPTNPSR1ALDH1A1TSHR
SCHEMBL15984907 0.80 KAT2B (0.97) KAT2BMAPTSMN1; SMN2POLBPKM
Hydrochloric Acid SCHEMBL513299 0.78 KAT2B (1.00) KAT2BMAPTPOLBPKMPRSS1
SCHEMBL15984903 0.77 KAT2B (0.79) KAT2BMAPTSMN1; SMN2POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1437123-B2 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'ORÉAL (FR) 2017-11-08 EP claimed
EP-0999823-B2 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME OREAL (FR) 2011-10-05 EP claimed
EP-1437123-B1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME OREAL (FR) 2007-06-06 EP claimed
EP-0999823-B1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME OREAL (FR) 2004-06-16 EP claimed
US-20030084516-A9 Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods L'OREAL S.A. (FR) 2003-05-08 US claimed
US-20030000023-A9 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'OREAL S.A. (FR) 2003-01-02 US claimed
US-20020095732-A1 Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods KRAVTCHENKO SYLVAIN (FR) 2002-07-25 US claimed
US-20020004956-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME RONDEAU CHRISTINE (FR) 2002-01-17 US claimed
US-20230139146-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE L'OREAL (FR) 2023-05-04 US disclosed
US-11166896-B2 Process for dyeing and relaxing curls of keratin fibres, using reducing agents and hair dyes, and associated kit L'OREAL (FR) 2021-11-09 US disclosed
EP-3558462-B1 PROCESS FOR DYEING AND RELAXING CURLS OF KERATIN FIBRES, USING REDUCING AGENTS AND HAIR DYES, AND ASSOCIATED KIT OREAL (FR) 2021-01-20 EP disclosed
US-20200085714-A1 Process for Dyeing and Relaxing Curls of Keratin Fibres, Using Reducing Agents and Hair Dyes, and Associated Kit L'OREAL (FR) 2020-03-19 US disclosed
EP-3086856-B1 PACKAGING ARTICLE COMPRISING AN ENVELOPE AND AN ANHYDROUS DYE COMPOSITION COMPRISING A DIRECT DYE, USE OF THE SAME AND PROCESS FOR DYEING KERATIN FIBRES OREAL (FR) 2019-05-15 EP disclosed
US-10130829-B2 Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use of the same and process for dyeing keratin fibres L'OREAL (FR) 2018-11-20 US disclosed
US-20170001045-A1 PACKAGING ARTICLE COMPRISING AN ENVELOPE AND AN ANHYDROUS DYE COMPOSITION COMPRISING A DIRECT DYE, USE OF THE SAME AND PROCESS FOR DYEING KERATIN FIBRES L'OREAL (FR) 2017-01-05 US disclosed
US-6712861-B2 CATIONIC DIRECT DYE L'OREAL S.A. (FR) 2004-03-30 US disclosed
US-20030084516-A9 Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods L'OREAL S.A. (FR) 2003-05-08 US disclosed
US-20030000023-A9 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'OREAL S.A. (FR) 2003-01-02 US disclosed
US-20020095732-A1 Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods KRAVTCHENKO SYLVAIN (FR) 2002-07-25 US disclosed
US-20020004956-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME RONDEAU CHRISTINE (FR) 2002-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030000023-A9 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME KRT18, CYB5R3, TUBB6 KAT2B 663/4885MAPT 834/4885NPSR1 3904/4885
US-20170001045-A1 PACKAGING ARTICLE COMPRISING AN ENVELOPE AND AN ANHYDROUS DYE COMPOSITION COMPRISING A DIRECT DYE, USE OF THE SAME AND PROCESS FOR DYEING KERATIN FIBRES KRT18, DLD, LPO KAT2B 958/4885MAPT 839/4885NPSR1 4503/4885
US-20200085714-A1 Process for Dyeing and Relaxing Curls of Keratin Fibres, Using Reducing Agents and Hair Dyes, and Associated Kit KRT18, KIT, KLK5 KAT2B 255/4885MAPT 752/4885NPSR1 4394/4885
US-20020095732-A1 Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods KRT18, PLOD1, PLOD2 KAT2B 566/4885MAPT 559/4885NPSR1 4151/4885
US-20230139146-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE KRT18, TPM3, PRKDC KAT2B 1064/4885MAPT 904/4885NPSR1 4708/4885
US-20030084516-A9 Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods KRT18, PLOD1, PLOD2 KAT2B 566/4885MAPT 559/4885NPSR1 4151/4885
US-10130829-B2 Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use of the same and process for dyeing keratin fibres KRT18, DLD, LPO KAT2B 958/4885MAPT 839/4885NPSR1 4503/4885
US-11166896-B2 Process for dyeing and relaxing curls of keratin fibres, using reducing agents and hair dyes, and associated kit KRT18, KIT, KLK5 KAT2B 255/4885MAPT 752/4885NPSR1 4394/4885
US-20020004956-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME KRT18, TUBB1, TUBB4B KAT2B 114/4885MAPT 522/4885NPSR1 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.