Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113403 | 0.89 | HDAC6 (0.59) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10115177 | 0.85 | HPGD (0.65) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10113511 | 0.85 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10114688 | 0.84 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10113497 | 0.82 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL10114981 | 0.82 | TP53 (0.55) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10115026 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LMNAHDAC6HDAC3HDAC4 | |
| SCHEMBL10115072 | 0.81 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10113440 | 0.81 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1LMNAHDAC6HDAC3 | |
| SCHEMBL10113642 | 0.80 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1LMNAHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | L3MBTL1 2541/4885ALDH1A1 4599/4885LMNA 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.