Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5088579 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL10486473 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL3629010 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5086677 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5088365 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5091618 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5085110 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL921149 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5091804 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 | |
| Bromide SCHEMBL5086826 | 1.00 | DNM1 (0.74) | DNM1TSHRTHRBBDKRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964457-A | Synthesis method of octafluoronaphthalene and synthesis method of 2-bromoheptafluoronaphthalene | 浙江大学衢州研究院 | 2024-05-03 | — | — | CN | claimed |
| CN-116948547-A | Novel white reinforced photovoltaic backboard base film, preparation method and application thereof | 宁波勤邦新材料科技股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-112795998-B | Preparation method of non-intrinsic flame-retardant high-strength polyester industrial yarn | 湖南美莱珀科技发展有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-112812285-B | Macromolecular flame retardant and preparation method and application thereof | 湖南美莱珀科技发展有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-112812285-A | Macromolecular flame retardant and preparation method and application thereof | 湖南美莱珀科技发展有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112795998-A | Preparation method of non-intrinsic flame-retardant high-strength polyester industrial yarn | 湖南美莱珀科技发展有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-108794727-B | A kind of degradable hyperbranched epoxy resin and preparation method thereof | 中南民族大学 | 2019-09-24 | — | — | CN | claimed |
| CN-109320688-A | A kind of high temperature resistant hyperbranched epoxy resin and preparation method thereof | 中南民族大学 | 2019-02-12 | — | — | CN | claimed |
| CN-108794727-A | A kind of degradable hyperbranched epoxy resin and preparation method thereof | 中南民族大学 | 2018-11-13 | — | — | CN | claimed |
| CN-107573511-A | A kind of aminated polyethers intermediate, the preparation method and application of its Phosphorylated products | 江苏苏博特新材料股份有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-102675707-A | Quaternary phosphonium salt montmorillonoid enhanced polyolefin nanocomposite and preparation method thereof | UNIV HENAN SCIENCE & TECH | 2012-09-19 | — | — | CN | claimed |
| US-5545768-A | Process for the preparation of chlorofluronitrobenzenes and difluoronitrobenzenes | HOECHET AG (DE) | 1996-08-13 | — | — | US | claimed |
| EP-0523671-B1 | Process for the preparation of chlorofluoronitrobenzenes | HOECHST AG (DE) | 1996-01-17 | — | — | EP | claimed |
| US-5463148-A | Process for the preparation of chlorofluoronitrobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0536175-B1 | PROCESS FOR PRODUCING CHLOROFLUORONITRO BENZENES AND DIFLUORONITRO BENZENES | HOECHST AG (DE) | 1995-09-20 | — | — | EP | claimed |
| US-5344738-A | Process of making toner compositions | XEROX CORPORATION (US) | 1994-09-06 | — | — | US | claimed |
| EP-0523671-A2 | Process for the preparation of chlorofluoronitrobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-20 | — | — | EP | claimed |
| US-12630518-B2 | Process for preparing 1,2-benzisothiazoline-3-one | THOR GMBH (DE) | 2026-05-19 | — | — | US | disclosed |
| US-4328170-A | Process for preparing an α-cyanoacrylate | MATSUMOTO SEIYAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4282167-A | IN A WATER INSOLUBLE ORGANIC SOLVENT WITH AN ALKALI METAL HYPOBROMITE | W. R. GRACE & CO. (US) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630518-B2 | Process for preparing 1,2-benzisothiazoline-3-one | CBR1, SULT1A1, ARSA | OPRM1 1088/4885DNM1 4597/4885TSHR 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.