SCHEMBL10114836

SCHEMBL10114836

C=C(C)C(=O)OCCC[Si](OCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](C)(C)CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)O[Si](C)(C)CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10115076 0.93 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL31539523 0.87 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL35807 0.86 TSHR (0.51) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL10793668 0.85 TSHR (0.43) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL9576597 0.85 TSHR (0.43) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL333002 0.85 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL10114803 0.84 TSHR (0.36) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9576331 0.84 TSHR (0.42) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL9576545 0.84 TSHR (0.42) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL30825544 0.84 TSHR (0.46) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383234-B2 Charging member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-02-26 US disclosed
US-20120141162-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-06-07 US disclosed