SCHEMBL35807

SCHEMBL35807

C=C(C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333002 0.98 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11312974 0.95 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL15856026 0.95 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9418354 0.95 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11312944 0.95 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL29583152 0.95 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11157535 0.95 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL397519 0.95 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2367984 0.94 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL14278962 0.94 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8179 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060384-A Ultraviolet light-moisture mixed curing coating composition and preparation method thereof 深圳职业技术大学 2026-05-19 CN claimed
CN-121610138-B Fluorine-free silicon-containing anti-icing coating regulated and controlled based on organic tellurium compound and preparation method thereof 西北工业大学 2026-05-19 CN claimed
CN-122043860-A Low-haze low-temperature curing negative photosensitive resin composition, preparation method thereof and hardening film 深圳市道尔顿电子材料股份有限公司 2026-05-15 CN claimed
CN-122037071-A High-moisturizing contact lens material and preparation method thereof 甘肃康视达科技集团有限公司 2026-05-15 CN claimed
CN-122037070-A Preparation method and application of acrylic acid-double bond-containing acyloxy silicone oil copolymerization smoothing agent 国科广化精细化工孵化器(南雄)有限公司 2026-05-15 CN claimed
CN-122037085-A Contact lens with high moisture retention and low water loss and preparation method thereof 甘肃康视达科技集团有限公司 2026-05-15 CN claimed
US-20260132232-A1 OPHTHALMIC DEVICES BAUSCH LOMB IRELAND LTD (IE) 2026-05-14 US claimed
CN-122011646-A Contact lens based on up-conversion luminescent nano material and preparation method thereof 甘肃康视丽隐形眼镜有限公司 2026-05-12 CN claimed
WO-2026089857-A1 METHOD OF PREPARING AND USING A SKIN CARE COMPOSITION DOW SILICONES CORPORATION (US) 2026-04-30 WO claimed
EP-2828317-B1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR PREPARATION THEREOF AND THIN FILMS CONTAINING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2026-04-29 EP claimed
US-4748224-A Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof Devou, Maureen J. (CA) 1988-05-31 US claimed
EP-0252603-A2 Adhesives for ceramics and processes for the bonding of ceramics using same MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-01-13 EP claimed
EP-0242080-A2 Copolymer compositions PARAGON OPTICAL INC (US) 1987-10-21 EP claimed
US-4661573-A INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE PARAGON OPTICAL INC. (US) 1987-04-28 US claimed
US-4543398-A Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-09-24 US claimed
US-4500695-A Silicone-vinyl acetate composition for contact lenses IVANI EDWARD J 1985-02-19 US claimed
EP-0127321-A1 Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-12-05 EP claimed
US-4410674-A Silicone-vinyl acetate composition for contact lenses IVANI EDWARD J 1983-10-18 US claimed
US-4400333-A Production of oxygen permeable contact lenses NEEFE OPTICAL LABORATORY 1983-08-23 US claimed
US-4306042-A Method of making a contact lens material with increased oxygen permeability KESLINKE JR., ANTHONY G. 1981-12-15 US claimed