Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35807 | 0.98 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11068065 | 0.95 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11075198 | 0.94 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL29583152 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11312974 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL15856026 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11312944 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9418354 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2369533 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11157535 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727985-A2 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | Acuity Polymers, Inc. (US) | 2026-04-22 | — | — | EP | claimed |
| US-20260103557-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | ACUITY POLYMERS INC (US) | 2026-04-16 | — | — | US | claimed |
| US-12600820-B2 | Photocurable composition with high silicon content | CANON KABUSHIKI KAISHA (JP) | 2026-04-14 | — | — | US | claimed |
| US-20250368802-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY | CANON KK (JP) | 2025-12-04 | — | — | US | claimed |
| US-12358933-B2 | Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | PIOCEL CO., LTD. (KR) | 2025-07-15 | — | — | US | claimed |
| CN-119823609-A | Feather sheet for simulating animals and preparation method thereof | 惠州市嘉源峰工艺制品有限公司 | 2025-04-15 | — | — | CN | claimed |
| US-20250109153-A1 | A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | PIOCEL CO., LTD. (KR) | 2025-04-03 | — | — | US | claimed |
| CN-119591809-A | High-water-content high-oxygen-permeability silicon hydrogel, contact lens and preparation method of contact lens | 甘肃天后光学科技有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119322429-B | Negative photoresist composition and application thereof | 西安瑞联新材料股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119322429-A | Negative photoresist composition and application thereof | 西安瑞联新材料股份有限公司 | 2025-01-17 | — | — | CN | claimed |
| US-5084537-A | Contact lenses from organosilicon monomers that are oxygen permeable | BAUSCH & LOMB, INCORPORATED (US) | 1992-01-28 | — | — | US | claimed |
| US-5002979-A | Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent | BAUSCH & LOMB INCORPORATED (US) | 1991-03-26 | — | — | US | claimed |
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | claimed |
| EP-0345994-A2 | Contact lenses and materials and methods of making same | PILKINGTON BARNES HIND, INC. (US) | 1989-12-13 | — | — | EP | claimed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | claimed |
| US-4826936-A | Silicone-containing contact lens material and contact lenses made thereof | POLYMER TECHNOLOGY CORP. (US) | 1989-05-02 | — | — | US | claimed |
| US-4766189-A | POLYMER FROM UNSATURATED SILICATE, LOWER ALKYL ESTER SILOXANE, ACRYLIC ESTER, FLUOROACRYLIC ESTER AND WETTING AGENT | FUSED KONTACTS OF CHICAGO, INC. (US) | 1988-08-23 | — | — | US | claimed |
| EP-0242080-A2 | Copolymer compositions | PARAGON OPTICAL INC (US) | 1987-10-21 | — | — | EP | claimed |
| US-4661573-A | INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE | PARAGON OPTICAL INC. (US) | 1987-04-28 | — | — | US | claimed |
| US-4424328-A | POLYMERS OF UNSATURATED MULTIFUNCTIONAL POLYSILOXANES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358933-B2 | Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | SPEN, SAE1, OSTC | TSHR 3556/4885THRB 3131/4885POLB 925/4885 |
| US-20260103557-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | SMCHD1, ITGB8, POT1 | TSHR 795/4885THRB 1458/4885POLB 2885/4885 |
| US-12600820-B2 | Photocurable composition with high silicon content | BIRC2, ACP1, IRS1 | TSHR 4173/4885THRB 4666/4885POLB 3409/4885 |
| US-20250109153-A1 | A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | SPEN, SAE1, SOST | TSHR 3789/4885THRB 3126/4885POLB 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.