Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676892 | 0.86 | HDAC8 (0.62) | HDAC8LOXL2MEN1ALDH1A1KMT2A | |
| SCHEMBL10327073 | 0.86 | HDAC8 (0.62) | HDAC8LOXL2MEN1ALDH1A1KMT2A | |
| SCHEMBL10327317 | 0.86 | HDAC8 (0.62) | HDAC8LOXL2MEN1ALDH1A1KMT2A | |
| SCHEMBL11764176 | 0.82 | LOXL2 (0.50) | HDAC8LOXL2ALDH1A1CASP1GAA | |
| SCHEMBL11682834 | 0.82 | HDAC8 (0.45) | HDAC8LOXL2GAACXCR4 | |
| Racemethionine SCHEMBL9838937 | 0.80 | HDAC8 (0.45) | HDAC8MTNR1AMTNR1BGAA | |
| SCHEMBL6132870 | 0.79 | HDAC8 (0.64) | HDAC8LOXL2MTNR1AMTNR1BHRH3 | |
| SCHEMBL11957559 | 0.75 | HDAC8 (0.53) | HDAC8LOXL2MTNR1AMTNR1BCYP2A6 | |
| SCHEMBL8079346 | 0.73 | CXCR4 (0.60) | HDAC8MEN1ALDH1A1CASP1KMT2A | |
| SCHEMBL8932685 | 0.72 | HDAC8 (0.53) | HDAC8LOXL2ALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114686464-A | Application of D-N-carbamyl hydrolase in production of D-tryptophan | 湖南引航生物科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | claimed |
| US-9957536-B2 | Mutants of hydantoinase | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-01 | — | — | US | claimed |
| EP-2780451-B1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-09-20 | — | — | EP | claimed |
| US-20150056667-A1 | MUTANTS OF HYDANTOINASE | EVONIK OPERATIONS GMBH (DE) | 2015-02-26 | — | — | US | claimed |
| EP-2780451-A1 | MUTANTS OF HYDANTOINASE | Evonik Industries AG (DE) | 2014-09-24 | — | — | EP | claimed |
| WO-2013072486-A1 | MUTANTS OF HYDANTOINASE | EVONIK INDUSTRIES AG (DE) | 2013-05-23 | — | — | WO | claimed |
| EP-1666588-B1 | NOVEL TRANSPORTER PROTEIN | AJINOMOTO KK (JP) | 2011-05-11 | — | — | EP | claimed |
| US-7320794-B2 | Transporter protein | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | claimed |
| US-20060183190-A1 | NOVEL TRANSPORTER PROTEIN | AJINOMOTO CO., INC. (JP) | 2006-08-17 | — | — | US | claimed |
| EP-1666588-A1 | NOVEL TRANSPORTER PROTEIN | Ajinomoto Co., Inc. (JP) | 2006-06-07 | — | — | EP | claimed |
| US-20050112729-A1 | Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid | AJINOMOTO CO., INC. (JP) | 2005-05-26 | — | — | US | claimed |
| EP-0159866-B1 | PROCESS FOR PRODUCTION OF L-AMINO ACIDS | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0159866-A2 | Process for production of L-amino acids | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-30 | — | — | EP | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | claimed |
| CN-114686464-B | Application of D-N-carbamyl hydrolase in production of D-tryptophan | 湖南引航生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115772513-A | D-carbamyl hydrolase mutant, gene, expression vector and application thereof | 江南大学 | 2023-03-10 | — | — | CN | disclosed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | disclosed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183190-A1 | NOVEL TRANSPORTER PROTEIN | SLC12A5, SLC12A2, HM13 | HDAC8 3241/4885LOXL2 2686/4885MEN1 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.