Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96600 | 0.83 | PPARG (0.48) | PPARGMAOACISD1MAPTALDH1A1 | |
| SCHEMBL1016492 | 0.81 | PPARG (0.57) | PPARGFFAR1PPARA | |
| SCHEMBL8932730 | 0.81 | FFAR1 (0.42) | HDAC8PPARGMAOACISD1MAPT | |
| SCHEMBL9573682 | 0.78 | PPARG (0.42) | HDAC8PPARGMAOACISD1MAPT | |
| SCHEMBL13846702 | 0.74 | PPARG (0.59) | PPARGMAOACISD1MAPTMAOB | |
| SCHEMBL13846716 | 0.74 | PPARG (0.49) | PPARGMAOACISD1MAPTMAOB | |
| SCHEMBL1011574 | 0.72 | HDAC8 (0.65) | HDAC8LOXL2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8981993 | 0.72 | KDM4E (0.53) | HDAC8MAPTALDH1A1 | |
| SCHEMBL8547054 | 0.72 | KDM4E (0.53) | HDAC8MAPTALDH1A1 | |
| SCHEMBL98544 | 0.72 | ALDH1A1 (0.49) | PPARGMAOACISD1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |