Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.51 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357764 | 1.00 | HDAC8 (0.57) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL12258527 | 0.90 | HDAC8 (0.47) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL10283637 | 0.86 | HDAC8 (0.56) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL18751777 | 0.86 | HDAC8 (0.56) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL1226583 | 0.86 | HDAC8 (0.56) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL1405670 | 0.86 | HDAC8 (0.56) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL13399577 | 0.86 | HDAC8 (0.56) | HDAC8GAAPLA2G10PLA2G5POLB | |
| SCHEMBL6704329 | 0.83 | PPARG (0.44) | HDAC8GAAPOLBCXCR4ADAMTS4 | |
| D-Phenylalanine SCHEMBL11422526 | 0.83 | SLC7A5 (0.58) | HDAC8GAA | |
| SCHEMBL8016017 | 0.81 | HDAC8 (0.39) | HDAC8GAAPLA2G10PLA2G5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118704113-B | Antibacterial polyester yarn based on graphene and preparation process thereof | 保利源(南通)实业有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-118704113-A | Antibacterial polyester yarn based on graphene and preparation process thereof | 保利源(南通)实业有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-116686826-A | Air slow-release sterilization gel and preparation method thereof | 河北鑫淘沅医药科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116514646-A | Preparation method of phenylpyruvic acid | 浙江昂利泰制药有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-114315619-B | Synthesis method of dimethoxy dopa | 山东泓瑞医药科技股份公司 | 2023-03-24 | — | — | CN | claimed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114315619-A | Synthetic method of 3- (3, 4-dimethoxyphenyl) -L-alanine | 山东泓瑞医药科技股份公司 | 2022-04-12 | — | — | CN | claimed |
| EP-3716966-A2 | ALPHA KETO ACID COMPOSITIONS FOR TREATING HYPO-ALBUMINEMIA | Hull, Edgar, L., Jr. (US) | 2020-10-07 | — | — | EP | claimed |
| US-20200281881-A1 | Alpha Keto Acid Compositions for Treating Hypo-Albuminemia | Hull, Jr., Edgar L. (US) | 2020-09-10 | — | — | US | claimed |
| CN-110268553-A | Flexible and shape-conforming cable-type alkali metal battery | 纳米技术仪器公司 | 2019-09-20 | — | — | CN | claimed |
| EP-0677585-A1 | Process for the production of D-alpha-amino acids | ENIRICERCHE S.p.A. (IT) | 1995-10-18 | — | — | EP | claimed |
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | claimed |
| EP-0159866-B1 | PROCESS FOR PRODUCTION OF L-AMINO ACIDS | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0151651-B1 | PROCESS FOR THE PREPARATION OF A STARTING MATERIAL FOR THE PRODUCTION OF PHENYLALANINE | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | claimed |
| EP-0159866-A2 | Process for production of L-amino acids | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-30 | — | — | EP | claimed |
| US-4549028-A | Process for the preparation of hydantoin precursor of phenylalanine | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-22 | — | — | US | claimed |
| EP-0151651-A1 | Process for the preparation of a starting material for the production of phenylalanine | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-21 | — | — | EP | claimed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |
| US-4016037-A | FERMENTING A HYDANTOIN COMPOUND WITH FLAVOBACTERIUM AMINOGENES OR ITS ENZYMES | AJINOMOTO CO., INC. (JA) | 1977-04-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281881-A1 | Alpha Keto Acid Compositions for Treating Hypo-Albuminemia | ALB, AADAT, BCAT2 | HDAC8 3921/4885GAA 1119/4885PLA2G10 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.