Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 8/20 | 0.47 |
| ▸ | PREP | P48147 | 8/20 | 0.47 |
| ▸ | DPP4 | P27487 | 10/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765611 | 1.00 | FAP (0.47) | FAPPREPDPP4DPP7KMT2A | |
| SCHEMBL3269005 | 1.00 | FAP (0.47) | FAPPREPDPP4DPP7KMT2A | |
| SCHEMBL23314866 | 0.85 | MEN1 (0.51) | FAPPREPDPP4KMT2ASMN1; SMN2 | |
| SCHEMBL1633733 | 0.85 | MEN1 (0.51) | FAPPREPDPP4KMT2ASMN1; SMN2 | |
| SCHEMBL8350270 | 0.81 | PREP (0.48) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL8253564 | 0.81 | DPP4 (0.44) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL8350007 | 0.81 | ACE (0.51) | FAPPREPDPP4 | |
| SCHEMBL18636997 | 0.81 | ACE (0.51) | FAPPREPDPP4 | |
| SCHEMBL8350809 | 0.81 | POLB (0.49) | FAPPREPDPP4DPP7SMN1; SMN2 | |
| SCHEMBL12824557 | 0.80 | PREP (0.43) | FAPPREPDPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2012087976-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-06-28 | — | — | WO | disclosed |