Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 4/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | PEPD | P12955 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18636997 | 0.88 | ACE (0.51) | LMNARAB9AFAPPREPDPP4 | |
| SCHEMBL17751443 | 0.88 | POLB (0.49) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL8350270 | 0.88 | PREP (0.48) | FAPPREPDPP4ACEDPP8 | |
| SCHEMBL8350007 | 0.88 | ACE (0.51) | LMNARAB9AFAPPREPDPP4 | |
| SCHEMBL6468703 | 0.88 | KLK5 (0.53) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL14235217 | 0.88 | KLK5 (0.53) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL18653084 | 0.87 | DPP4 (0.49) | FAPPREPDPP4 | |
| SCHEMBL17751419 | 0.87 | POLB (0.48) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL6376807 | 0.84 | POLB (0.51) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL15457808 | 0.84 | PREP (0.42) | FAPPREPDPP4ACEDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |
| WO-2003099274-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |