SCHEMBL1011734

SCHEMBL1011734

Nc1ccc(-c2ccc(N)c(C(F)(F)F)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.63
GLA P06280 1/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
CYP3A4 P08684 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
TAAR1 Q96RJ0 2/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
AR P10275 2/20 0.40
HSD17B10 Q99714 1/20 0.39
PDK2 Q15119 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
FFAR4 Q5NUL3 2/20 0.38
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28831861 0.98 KIF11 (0.61) KIF11GLAPOLBGAATSHR
SCHEMBL349356 0.91 KIF11 (0.50) KIF11GLAPOLBGAATSHR
SCHEMBL29403371 0.91 KIF11 (0.50) KIF11GLAPOLBGAATSHR
Hydrochloric Acid SCHEMBL8644024 0.89 KIF11 (0.48) KIF11GLAPOLBGAATSHR
SCHEMBL3789405 0.86 KIF11 (0.48) KIF11GAATDP1CYP3A4ALDH1A1
SCHEMBL8922815 0.83 KIF11 (0.54) KIF11GLAPOLBGAATSHR
SCHEMBL3784954 0.83 KIF11 (0.69) KIF11GLAPOLBGAATSHR
SCHEMBL7625612 0.83 CYP3A4 (0.50) KIF11TSHRTDP1CYP3A4ALDH1A1
SCHEMBL2924757 0.82 KIF11 (0.53) KIF11CYP3A4PIK3CD
SCHEMBL3792886 0.82 MAOA (0.50) KIF11GLAPOLBGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114846082-B Resin composition and film 株式会社钟化 2024-07-12 CN claimed
CN-118339218-A Film, method for producing the same, and image display device 株式会社钟化 2024-07-12 CN claimed
CN-114072451-B Polyamic acid composition, method for preparing the same, and polyimide containing the same PI尖端素材株式会社 2024-07-02 CN claimed
CN-118255988-A Polyimide molded article and method for producing same 聚酰亚胺先端材料有限公司 2024-06-28 CN claimed
CN-118265740-A Polyimide powder with improved electrical conductivity using graphene and method for preparing same PI尖端素材株式会社 2024-06-28 CN claimed
CN-118215713-A Resin composition, molded article and film 株式会社钟化 2024-06-18 CN claimed
CN-118184603-A Diamine monomer containing piperazine unit, polyimide acid salt separation membrane, and preparation method and application thereof 天津科技大学 2024-06-14 CN claimed
CN-118159600-A Polyamic acid composition and preparation method thereof PI尖端素材株式会社 2024-06-07 CN claimed
CN-118147820-A Organic polymer nano composite fiber shrink film, preparation method thereof and application thereof in preparing wound dressing 山东大学 2024-06-07 CN claimed
CN-118159588-A Polyamic acid, polyamic acid composition, polyimide film, laminate, method for producing laminate, and electronic device 株式会社钟化 2024-06-07 CN claimed
CN-102110617-A Interposer films useful in semiconductor packaging applications, and methods relating thereto DU PONT 2011-06-29 CN claimed
US-20110143145-A1 Composition and Method for Corrosion Protection of a Structure THE BOEING COMPANY (US) 2011-06-16 US claimed
CN-102074480-A Thin film transistor compositions, and methods relating thereto DU PONT 2011-05-25 CN claimed
EP-2271692-A2 COMPOSITION AND METHOD FOR CORROSION PROTECTION OF A STRUCTURE The Boeing Company (US) 2011-01-12 EP claimed
US-20090263664-A1 COMPOSITION AND METHOD FOR CORROSION PROTECTION OF A STRUCTURE THE BOEING COMPANY (US) 2009-10-22 US claimed
WO-2009129206-A2 COMPOSITION AND METHOD FOR CORROSION PROTECTION OF A STRUCTURE THE BOEING COMPANY (US) 2009-10-22 WO claimed
US-20080096027-A1 TOUGH AND STRONGLY-ADHERENT ANTI-ICING COATINGS THE BOEING COMPANY (US) 2008-04-24 US claimed
EP-0656560-B1 Liquid crystal display with patterned retardation films GUARDIAN INDUSTRIES (US) 2004-08-04 EP claimed
EP-0656560-A2 Liquid crystal display with patterned retardation films OIS Optical Imaging Systems, Inc. (US) 1995-06-07 EP claimed
US-5310863-A Polyimide materials with improved physico-chemical properties INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-05-10 US claimed