Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265822 | 0.86 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL2785652 | 0.86 | MCL1 (0.40) | MAPTALDH1A1MCL1LMNAATM | |
| Alcohol SCHEMBL28286197 | 0.79 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8183232 | 0.77 | ALDH1A1 (0.45) | HSD17B10MAPTALDH1A1MCL1LMNA | |
| SCHEMBL148546 | 0.77 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL12158758 | 0.77 | MGAM (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL286783 | 0.77 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL14532417 | 0.77 | MGAM (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL12268201 | 0.77 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL12534384 | 0.77 | TSHR (0.37) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119742-B2 | Multi-armed catechol compound blends | KNC NER ACQUISITION SUB, INC. (US) | 2012-02-21 | — | — | US | disclosed |