SCHEMBL148546

SCHEMBL148546

COC(=O)CC(C)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
HSD17B10 Q99714 2/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.36
BHMT Q93088 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
KCNA5 P22460 1/20 0.36
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL286783 1.00 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL12268201 1.00 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL28861626 0.98 TSHR (0.41) TSHRHSD17B10MGAMGAASI
SCHEMBL265822 0.90 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL30884920 0.85 ALDH1A1 (0.35) TSHRHSD17B10ALDH1A1KDM4EBHMT
Alcohol SCHEMBL28286197 0.83 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL316476 0.83 SLC22A6 (0.38) HSD17B10ALDH1A1KDM4EBHMTSLC22A6
SCHEMBL258152 0.82 SLC22A6 (0.50) TSHRALDH1A1BHMTSLC22A6MAPT
SCHEMBL12158758 0.81 MGAM (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL14532417 0.81 MGAM (0.50) TSHRHSD17B10MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118223049-B Micro-reaction process and system for electrolytically synthesizing musk ketone precursor by using circulating flow 宏济堂制药(商河)有限公司 2024-09-17 CN claimed
CN-118223049-A Micro-reaction process and system for electrolytically synthesizing musk ketone precursor by using circulating flow 宏济堂制药(商河)有限公司 2024-06-21 CN claimed
CN-108383723-B Preparation method of beta-methyl glutarate monomethyl ester with high purity and high yield 淄博职业学院 2021-03-23 CN claimed
CN-107337592-B Method for synthesizing muscone by using beta-methyl glutarate monomethyl ester 辽宁科技学院 2020-11-13 CN claimed
CN-108383723-A The preparation method of high-purity, high yield Beta-methyl monomethyl glutarate 淄博职业学院 2018-08-10 CN claimed
CN-108107125-A A kind of content assaying method of Beta-methyl monomethyl glutarate 山东宏济堂制药集团股份有限公司 2018-06-01 CN claimed
CN-107337592-A Utilize the method for β methylglutaric acid mono-methyl musk ambrette ketone 辽宁科技学院 2017-11-10 CN claimed
US-20260055097-A9 NRF2 PROTEIN DEGRADERS GANYMEDE ONCOLOGY INC (US) 2026-02-26 US disclosed
US-20250145611-A1 NRF2 PROTEIN DEGRADERS GANYMEDE ONCOLOGY, INC. 2025-05-08 US disclosed
EP-4543439-A2 NRF2 PROTEIN DEGRADERS Ganymede Oncology, Inc. (US) 2025-04-30 EP disclosed
CN-119804716-A Central control detection method for electrolytic reaction of synthetic musk ketone precursor 宏济堂制药(商河)有限公司 2025-04-11 CN disclosed
CN-119730847-A NRF2 protein degradation agent 盖尼米德肿瘤学股份有限公司 2025-03-28 CN disclosed
US-20240360149-A1 COMPOUND WITH ANTICANCER ACTIVITY KYOWA KIRIN CO., LTD. (JP) 2024-10-31 US disclosed
EP-0713420-A1 CARTRIDGE FILTER WITH INSOLUBLE ENZYME PARTICULATES CONTAINED THEREON MINNESOTA MINING & MFG (US) 1996-05-29 EP disclosed
US-5478466-A Multilayer comprising porous fibrous layer and immobilized enzyme catalyst powder top layer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-12-26 US disclosed
WO-1995005233-A1 CARTRIDGE FILTER WITH INSOLUBLE ENZYME PARTICULATES CONTAINED THEREON MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-23 WO disclosed
US-5262313-A Reaction of carrageen with esterase and hardening drops ANDCARE, INC. (US) 1993-11-16 US disclosed
US-5144021-A Reticulated cellulose and methods and microorganisms for the production thereof WEYERHAEUSER COMPANY (US) 1992-09-01 US disclosed
US-5079162-A High purity Acetobacter, cellulose with high tensile strength WEYERHAEUSER COMPANY (US) 1992-01-07 US disclosed
US-4863565-A Sheeted products formed from reticulated microbial cellulose WEYERHAEUSER COMPANY (US) 1989-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055097-A9 NRF2 PROTEIN DEGRADERS KEAP1, NFE2L2, NFE2 TSHR 2615/4885HSD17B10 346/4885MGAM 3637/4885
US-20250145611-A1 NRF2 PROTEIN DEGRADERS KEAP1, NFE2L2, NFE2 TSHR 2255/4885HSD17B10 2063/4885MGAM 3115/4885
US-20240360149-A1 COMPOUND WITH ANTICANCER ACTIVITY TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC2 TSHR 4169/4885HSD17B10 2015/4885MGAM 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.