Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 3/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | FGF1 | P05230 | 2/20 | 0.32 |
| ▸ | FGF2 | P09038 | 2/20 | 0.32 |
| ▸ | VEGFA | P15692 | 2/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26273822 | 0.88 | PDPK1 (0.40) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL769692 | 0.87 | PDPK1 (0.39) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL17773520 | 0.87 | PDPK1 (0.39) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL14850038 | 0.87 | PDPK1 (0.39) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL769799 | 0.85 | SSTR1 (0.47) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL18573702 | 0.82 | PDPK1 (0.43) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL26349596 | 0.82 | SSTR5 (0.39) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL14616695 | 0.82 | PDPK1 (0.37) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL10148767 | 0.81 | PDPK1 (0.42) | PDPK1MTORTACR2SSTR1SSTR2 | |
| SCHEMBL26349599 | 0.81 | PDPK1 (0.38) | PDPK1MTORTACR2SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021515-A1 | OLIGOMERIC COMPOUNDS AND METHODS | ISIS PHARMACEUTICALS, INC. | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021515-A1 | OLIGOMERIC COMPOUNDS AND METHODS | HNRNPH1, RNASEH1, SNRPE | PDPK1 4389/4885MTOR 4475/4885TACR2 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.