SCHEMBL26349596

SCHEMBL26349596

CC[C@H]1OC(OCc2ccccc2)[C@H](F)[C@@H](OCc2ccccc2)[C@@H]1C

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 2/20 0.39
SSTR1 P30872 1/20 0.39
SSTR2 P30874 1/20 0.39
SSTR4 P31391 1/20 0.39
SSTR3 P32745 1/20 0.39
FGF1 P05230 2/20 0.38
FGF2 P09038 2/20 0.38
VEGFA P15692 2/20 0.38
HPSE Q9Y251 2/20 0.38
BCHE P06276 1/20 0.37
SLC6A2 P23975 1/20 0.37
PDPK1 O15530 1/20 0.35
MTOR P42345 1/20 0.35
PTPN1 P18031 4/20 0.34
CDC25B P30305 4/20 0.34
GJB2 P29033 1/20 0.34
NT5E P21589 1/20 0.34
TACR2 P21452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26349606 0.88 SLC6A2 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL14667229 0.87 SSTR1 (0.44) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL26349603 0.87 LMNA (0.41) BCHESLC6A2PDPK1MTORNT5E
SCHEMBL26349588 0.87 LMNA (0.41) BCHESLC6A2PDPK1MTORNT5E
SCHEMBL26349591 0.87 LMNA (0.41) BCHESLC6A2PDPK1MTORNT5E
SCHEMBL26349599 0.85 PDPK1 (0.38) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL26349592 0.85 PDPK1 (0.38) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL18328600 0.85 FGF1 (0.43) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL15504369 0.85 FGF1 (0.43) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL769799 0.84 SSTR1 (0.47) SSTR5SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303618-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF REYOUNG CORPORATION (US) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303618-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF TLR9, XIAP, ENPP2 SSTR5 2945/4885SSTR1 4385/4885SSTR2 3807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.