Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224486 | 0.93 | AADAT (0.46) | AADATPREPTMEM97SIGMAR1TGM2 | |
| SCHEMBL3224476 | 0.93 | AADAT (0.46) | AADATPREPTMEM97SIGMAR1TGM2 | |
| SCHEMBL3264198 | 0.84 | SMN1; SMN2 (0.46) | AADATPREPTMEM97SIGMAR1 | |
| SCHEMBL3264197 | 0.84 | SMN1; SMN2 (0.46) | AADATPREPTMEM97SIGMAR1 | |
| SCHEMBL10117332 | 0.83 | AADAT (0.43) | AADATPREPTMEM97SIGMAR1NPSR1 | |
| SCHEMBL3214970 | 0.82 | ENPP2 (0.47) | AADATPREPTMEM97SIGMAR1SCD5 | |
| SCHEMBL3200657 | 0.82 | ENPP2 (0.47) | AADATPREPTMEM97SIGMAR1SCD5 | |
| SCHEMBL3215248 | 0.81 | ENPP2 (0.43) | AADATSCD5 | |
| SCHEMBL3215257 | 0.81 | ENPP2 (0.43) | AADATSCD5 | |
| SCHEMBL38656320 | 0.81 | KMT2A (0.54) | ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087976-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-06-28 | — | — | WO | disclosed |