SCHEMBL101181

SCHEMBL101181

COCCOC(=O)CCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.43
GAA P10253 4/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
MAOB P27338 3/20 0.39
MAOA P21397 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
AGTR1 P30556 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ACHE P22303 1/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
APP P05067 1/20 0.36
NTRK1 P04629 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101256 0.97 ALOX5 (0.41) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL3413677 0.97 ALOX5 (0.41) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL3287819 0.97 ALOX5 (0.41) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL100778 0.97 ALOX5 (0.41) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL10135978 0.96 ALOX5 (0.44) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL100357 0.93 ALOX5 (0.42) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL16623979 0.93 ALOX5 (0.42) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL104649 0.93 ALOX5 (0.42) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL672759 0.92 ALOX5 (0.41) ALOX5GAAKMT2AMEN1MAOB
SCHEMBL31361790 0.92 ALOX5 (0.41) ALOX5GAAKMT2AMEN1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267523-A2 Stabilized electrochromic media BASF SE (DE) 2010-12-29 EP claimed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US claimed
EP-1789842-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-05-30 EP claimed
WO-2006005691-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-19 WO claimed
US-20060007519-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2006-01-12 US claimed
EP-1896550-B1 STABILIZED ELECTROCHROMIC MEDIA BASF SE (DE) 2013-08-14 EP disclosed
US-20120058974-A1 Composition comprising pesticide and benzotriazole UV absorbers BASF SE (DE) 2012-03-08 US disclosed
EP-2267523-A2 Stabilized electrochromic media BASF SE (DE) 2010-12-29 EP disclosed
US-7718096-B2 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-18 US disclosed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US disclosed
EP-1896550-A1 STABILIZED ELECTROCHROMIC MEDIA Ciba Specialty Chemicals Holding Inc. (CH) 2008-03-12 EP disclosed
EP-1789842-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-05-30 EP disclosed
WO-2007003508-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-11 WO disclosed
US-20070002423-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2007-01-04 US disclosed
WO-2006005691-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-19 WO disclosed
US-20060007519-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058974-A1 Composition comprising pesticide and benzotriazole UV absorbers DDT, CRY1, PAH ALOX5 3015/4885GAA 399/4885KMT2A 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.