SCHEMBL10119182

SCHEMBL10119182

BC1=NN(c2ncccc2Cl)C(C(=O)Nc2c(C)cc(Cl)cc2C(=O)NC)C1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 16/20 0.46
DRD4 P21917 1/20 0.36
TRPV1 Q8NER1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13473989 0.94 MALT1 (0.40) MALT1DRD4TRPV1
SCHEMBL13208793 0.93 MALT1 (0.44) MALT1TRPV1
SCHEMBL11888068 0.93 MALT1 (0.41) MALT1DRD4TRPV1
SCHEMBL13356325 0.92 MALT1 (0.44) MALT1DRD4TRPV1
SCHEMBL9290211 0.92 MALT1 (0.44) MALT1DRD4TRPV1
SCHEMBL1148344 0.91 MALT1 (0.44) MALT1DRD4TRPV1
SCHEMBL1148395 0.90 MALT1 (0.43) MALT1DRD4
SCHEMBL13242829 0.89 MALT1 (0.42) MALT1DRD4
SCHEMBL9290237 0.88 MALT1 (0.41) MALT1DRD4TRPV1
SCHEMBL9290198 0.86 MALT1 (0.40) MALT1DRD4TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2274981-B1 Synergistic mixtures for controlling invertebrate pests containing an anthranilamide compound and fipronil DU PONT (US) 2012-12-26 EP disclosed
EP-2060180-B1 Synergistic mixtures of anthranilamide invertebrate pest control agents DU PONT (US) 2012-02-22 EP disclosed
WO-2008101682-A2 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-08-28 WO disclosed