SCHEMBL1148395

SCHEMBL1148395

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)C1CC(Br)=NN1c1ncccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 13/20 0.43
DHODH Q02127 1/20 0.36
PHGDH O43175 1/20 0.35
DRD4 P21917 1/20 0.34
GRM4 Q14833 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290241 0.93 MALT1 (0.41) MALT1DHODHPHGDHGRM4
SCHEMBL9289357 0.93 MALT1 (0.39) MALT1DHODHPHGDH
SCHEMBL13002825 0.92 MALT1 (0.40) MALT1DHODHPHGDHGRM4
SCHEMBL9290071 0.92 MALT1 (0.42) MALT1DHODH
SCHEMBL12438369 0.92 MALT1 (0.40) MALT1DHODHPHGDHGRM4
SCHEMBL9290211 0.91 MALT1 (0.44) MALT1DRD4GRM4
SCHEMBL13356325 0.91 MALT1 (0.44) MALT1DRD4GRM4
SCHEMBL10286763 0.91 MALT1 (0.44) MALT1DHODHPHGDHDRD4
SCHEMBL10119182 0.90 MALT1 (0.46) MALT1DRD4
SCHEMBL1148344 0.90 MALT1 (0.44) MALT1DRD4GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
EP-2263460-B1 Synergistic mixtures for controlling invertebrate pests containing an anthranilamide compound and esfenvalerate DU PONT (US) 2012-10-24 EP disclosed
EP-2263459-B1 Synergistic mixtures for controlling invertebrate pests containing an anthranilamide compound and indoxacarb DU PONT (US) 2012-10-24 EP disclosed
EP-2197844-B1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-07-25 EP disclosed
WO-2012092827-A1 CHEMICAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2012-07-12 WO disclosed
EP-2471364-A1 Ternary fungicidal compositions comprising sedaxane Syngenta Participations AG (CH) 2012-07-04 EP disclosed
WO-2012069008-A1 3-SUBSTITUTED SPIROHETEROCYCLIC FURAN AND THIOFURAN DIONE DERIVATIVES USEFUL AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-05-31 WO disclosed
EP-2060181-B1 Synergistic mixtures of anthranilamide invertebrate pest control agents DU PONT (US) 2012-05-16 EP disclosed
EP-2060180-B1 Synergistic mixtures of anthranilamide invertebrate pest control agents DU PONT (US) 2012-02-22 EP disclosed
EP-2193715-A1 Fungicidal Compositions Sygenta Participations AG. (CH) 2010-06-09 EP disclosed
EP-2193714-A1 Fungicidal Compositions Sygenta Participations AG. (CH) 2010-06-09 EP disclosed
EP-2193717-A1 Fungicidal Compositions Sygenta Participations AG. (CH) 2010-06-09 EP disclosed
WO-2009090038-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2009-07-23 WO disclosed
WO-2009049851-A1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-04-23 WO disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 WO disclosed
WO-2009021717-A2 PESTICIDAL FORMULATION SYNGENTA PARTICIPATIONS AG (CH) 2009-02-19 WO disclosed
WO-2009010260-A2 CONDENSED ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-01-22 WO disclosed
EP-1819695-B1 ANTHRANILAMIDE DERIVATIVES AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-12-17 EP disclosed
WO-2008064891-A1 N-CYANOALKYLANTHRANILAMIDES AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-06-05 WO disclosed