Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 7/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118862 | 0.88 | PSMB5 (0.56) | PSMB5CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL10118970 | 0.88 | PSMB5 (0.56) | PSMB5CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL10119206 | 0.84 | CTSL (0.61) | PSMB5CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL10118811 | 0.83 | CTSB (0.57) | PSMB5CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL10118845 | 0.83 | CTSB (0.52) | PSMB5CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL10118851 | 0.83 | CTSB (0.52) | PSMB5CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL10118849 | 0.81 | HPGD (0.56) | PSMB5CTSLCTSBHPGDKMT2A | |
| SCHEMBL10118869 | 0.81 | PSMB5 (0.48) | PSMB5CTSLCTSSCTSKCTSB | |
| SCHEMBL10118968 | 0.81 | CTSL (0.50) | PSMB5CTSLCTSSCTSKCTSB | |
| SCHEMBL10118859 | 0.81 | CTSL (0.51) | PSMB5CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |