Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16741983 | 0.90 | SCN3A (0.52) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL16741981 | 0.90 | SCN3A (0.52) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| SCHEMBL845510 | 0.89 | SCN3A (0.54) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| SCHEMBL2707503 | 0.86 | SCN3A (0.54) | SCN3ASCN9APSMB8 | |
| SCHEMBL10119360 | 0.82 | HDAC3 (0.43) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| SCHEMBL2172641 | 0.82 | HPGD (0.56) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| SCHEMBL9352214 | 0.82 | HPGD (0.56) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| SCHEMBL2392383 | 0.82 | HPGD (0.56) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL4306381 | 0.80 | SCN3A (0.56) | SCN3ASCN9AHDAC1HDAC3HDAC4 | |
| SCHEMBL17676966 | 0.79 | SCN3A (0.59) | PTPN1SCN3ASCN9AHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |