SCHEMBL2392383

SCHEMBL2392383

O=C(Nc1ccccc1)[C@@H]1CCCN1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
SCN3A Q9NY46 2/20 0.54
SCN9A Q15858 1/20 0.54
POLB P06746 1/20 0.54
PSMB8 P28062 2/20 0.53
CTSC P53634 1/20 0.51
KHK P50053 1/20 0.51
DPP4 P27487 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
GFER P55789 1/20 0.50
KMT2A Q03164 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2172641 1.00 HPGD (0.56) HPGDSCN3ASCN9APOLBPSMB8
SCHEMBL9352214 1.00 HPGD (0.56) HPGDSCN3ASCN9APOLBPSMB8
Hydrochloric Acid SCHEMBL4306381 0.98 SCN3A (0.56) HPGDSCN3ASCN9APOLBPSMB8
SCHEMBL516052 0.95 HPGD (0.58) HPGDSCN3ASCN9APOLBPSMB8
SCHEMBL13708499 0.95 HPGD (0.58) HPGDSCN3ASCN9APOLBPSMB8
Hydrochloric Acid SCHEMBL3266984 0.94 HPGD (0.57) HPGDSCN3ASCN9APOLBPSMB8
SCHEMBL7072835 0.91 HPGD (0.56) HPGDPOLBDPP4GAAMAPT
SCHEMBL7072829 0.91 HPGD (0.56) HPGDPOLBDPP4GAAMAPT
SCHEMBL1752153 0.91 SCN3A (0.59) HPGDSCN3ASCN9APSMB8CTSC
SCHEMBL17676966 0.91 SCN3A (0.59) HPGDSCN3ASCN9APSMB8CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115616050-B Preparation method and application of vanadium battery electrolyte ion concentration sensor material 杭州德海艾科能源科技有限公司 2023-04-07 CN claimed
CN-115616050-A Preparation method and application of vanadium battery electrolyte ion concentration sensor material 杭州德海艾科能源科技有限公司 2023-01-17 CN claimed
EP-4604951-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF AMIRA THERAPEUTICS, S.L. (ES) 2025-08-27 EP disclosed
WO-2024083861-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF SELABTEC SCIENCES, SLU (ES) 2024-04-25 WO disclosed
EP-4356909-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF Selabtec Sciences, SLU (ES) 2024-04-24 EP disclosed
CN-117659018-A Chiral C1 symmetrical imidazole-pyridine-imidazolidinone tridentate nitrogen ligand, synthesis and application thereof 河南师范大学 2024-03-08 CN disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
CN-115616050-B Preparation method and application of vanadium battery electrolyte ion concentration sensor material 杭州德海艾科能源科技有限公司 2023-04-07 CN disclosed
CN-115616050-A Preparation method and application of vanadium battery electrolyte ion concentration sensor material 杭州德海艾科能源科技有限公司 2023-01-17 CN disclosed
EP-3819295-A1 STEREOSELECTIVE SYNTHESIS OF ENANTIOMERICALLY-ENRICHED PANTOLACTONE DSM IP Assets B.V. (NL) 2021-05-12 EP disclosed
EP-0346847-B1 Amino acid derivatives HOFFMANN LA ROCHE (CH) 1994-05-11 EP disclosed
US-5310491-A Alkyl substituted 1,2-dihydroquinoline reacted with diarylamine UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-05-10 US disclosed
EP-0346847-A2 Amino acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-12-20 EP disclosed
US-4636567-A CNS DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-01-13 US disclosed
US-4610821-A CENTRAL NERVOUS SYSTEM, THYROTROPIN RELEASING HORMONE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-09-09 US disclosed
US-4564609-A NERVOUS SYSTEM DISORDERS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-01-14 US disclosed
US-4562197-A CATTLE, POULTRY PFIZER INC. (US) 1985-12-31 US disclosed
EP-0144230-A2 Growth promotants for animals Pfizer Limited (GB) 1985-06-12 EP disclosed
EP-0123444-A1 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS HPGD 905/4885SCN3A 1263/4885SCN9A 2665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.