Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.37 |
| ▸ | ABAT | P80404 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119391 | 0.83 | ALDH1A1 (0.46) | KDM4ERAB9AALDH1A1GAAHPGD | |
| SCHEMBL10106319 | 0.81 | ALDH1A1 (0.45) | PTGS2KDM4ERAB9AALDH1A1GAA | |
| SCHEMBL10106334 | 0.81 | KDM4E (0.43) | PTGS2KDM4ERAB9AALDH1A1GAA | |
| SCHEMBL10176595 | 0.81 | ALDH1A1 (0.39) | PTGS2KDM4ERAB9AALDH1A1SLC6A4 | |
| SCHEMBL10106351 | 0.79 | ALDH1A1 (0.51) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL7074379 | 0.78 | KDM4E (0.50) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL10106344 | 0.78 | RAB9A (0.43) | PTGS2KDM4ERAB9AALDH1A1GAA | |
| SCHEMBL10106450 | 0.77 | ALDH1A1 (0.40) | PTGS2KDM4ERAB9AALDH1A1ALDH5A1 | |
| SCHEMBL10106385 | 0.77 | ALDH1A1 (0.44) | PTGS2KDM4ERAB9AALDH1A1GAA | |
| SCHEMBL10106338 | 0.77 | ALDH1A1 (0.48) | PTGS2KDM4ERAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321739-B2 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | MICRODOSE THERAPEUTX, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-8119672-B2 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | MICRODOSE THERAPEUTX, INC. (US) | 2012-02-21 | — | — | US | disclosed |