SCHEMBL10119429

SCHEMBL10119429

CC(C)C(C/C=C/Cl)C(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28626659 1.00 GRIK1 (0.36) GRIK1GRIK2
SCHEMBL3355253 0.89 SLC1A3 (0.32)
SCHEMBL3355257 0.89 SLC1A3 (0.32)
SCHEMBL622161 0.83 GRIK1 (0.44) GRIK1GRIK2
SCHEMBL5002016 0.83 GRIK1 (0.44) GRIK1GRIK2
SCHEMBL2232483 0.83 GRIK1 (0.44) GRIK1GRIK2
SCHEMBL5264845 0.83 GRIK1 (0.44) GRIK1GRIK2
SCHEMBL622162 0.83 GRIK1 (0.44) GRIK1GRIK2
SCHEMBL5264842 0.83 GRIK1 (0.44) GRIK1GRIK2
SCHEMBL2232479 0.83 GRIK1 (0.44) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113387828-A Preparation method of aliskiren intermediate 江巨东 2021-09-14 CN disclosed
CN-113387828-A Preparation method of aliskiren intermediate 江巨东 2021-09-14 CN disclosed
WO-2012021446-A2 PROCESS FOR PREPARING ALISKIREN AND ITS INTERMEDIATES DR. REDDY'S LABORATORIES LTD. (IN) 2012-02-16 WO disclosed