Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264842 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2232483 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5002016 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL622161 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5264845 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL622162 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2031192 | 0.86 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8101229 | 0.86 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2035309 | 0.86 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6871010 | 0.86 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387828-A | Preparation method of aliskiren intermediate | 江巨东 | 2021-09-14 | — | — | CN | claimed |
| EP-1571138-B2 | PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF | ASAHI GLASS CO LTD (JP) | 2014-12-17 | — | — | EP | claimed |
| EP-1961728-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ACID OR BASIC AMINO ACID SALT THEREOF | ASAHI GLASS CO LTD (JP) | 2013-12-11 | — | — | EP | claimed |
| WO-2011148392-A1 | PROCESS FOR THE PREPARATION OF (2S,4S,5S,7S)-N-(2-CARBAMYL-2- METHYLPROPYL)-5-AMINO-4-HYDROXY-2,7-DIISOPROPYL-8-[4-METHOXY-3-(3- METHOXYPROPOXY)PHENYL]-OCTANAMIDE HEMIFUMARATE AND ITS INTERMEDIATES THEREOF | MSN LABORATORIES LIMITED (IN) | 2011-12-01 | — | — | WO | claimed |
| CN-101331104-A | Method for producing optically active (4E)-5-chloro-2-isopropyl-4-pentenoic acid or basic amino acid salt thereof | ASAHI GLASS COMPANY LIMTED (JP) | 2008-12-24 | — | — | CN | claimed |
| US-20080255385-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ACID OR BASIC AMINO ACID SALT THEREOF | ASAHI GLASS COMPANY, LIMTED (JP) | 2008-10-16 | — | — | US | claimed |
| EP-1961728-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ACID OR BASIC AMINO ACID SALT THEREOF | Asahi Glass Co., Ltd. (JP) | 2008-08-27 | — | — | EP | claimed |
| WO-2008006394-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE (4E)-5- HALO-2-ALKYLPENT-4-ENOIC ACIDS AND THEIR ESTER DERIVATIVES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2008-01-17 | — | — | WO | claimed |
| US-7232925-B2 | Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof | ASAHI GLASS COMPANY, LIMITED (JP) | 2007-06-19 | — | — | US | claimed |
| EP-1571138-B1 | PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF | ASAHI GLASS CO LTD (JP) | 2007-02-28 | — | — | EP | claimed |
| US-20050228193-A1 | Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof | ASAHI GLASS COMPANY LIMITED (JP) | 2005-10-13 | — | — | US | claimed |
| EP-1571138-A1 | PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF | ASAHI GLASS COMPANY LTD. (JP) | 2005-09-07 | — | — | EP | claimed |
| CN-116924928-A | Preparation method of aliskiren intermediate | 江苏阿尔法药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-113387828-A | Preparation method of aliskiren intermediate | 江巨东 | 2021-09-14 | — | — | CN | disclosed |
| CN-113387828-A | Preparation method of aliskiren intermediate | 江巨东 | 2021-09-14 | — | — | CN | disclosed |
| US-9309503-B2 | Preparation of an esterase | DPX HOLDINGS B.V. (NL) | 2016-04-12 | — | — | US | disclosed |
| US-20050228193-A1 | Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof | ASAHI GLASS COMPANY LIMITED (JP) | 2005-10-13 | — | — | US | disclosed |
| US-20050228193-A1 | Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof | ASAHI GLASS COMPANY LIMITED (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-1571138-A1 | PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF | ASAHI GLASS COMPANY LTD. (JP) | 2005-09-07 | — | — | EP | disclosed |
| EP-1571138-A1 | PROCESSES FOR PRODUCING (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ESTER AND OPTICALLY ACTIVE ISOMER THEREOF | ASAHI GLASS COMPANY LTD. (JP) | 2005-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228193-A1 | Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof | C5, ALOX5, PTGER4 | GRIK1 2747/4885GRIK2 2313/4885SLC1A3 4112/4885 |
| US-20080255385-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ACID OR BASIC AMINO ACID SALT THEREOF | PLAAT5, ELOVL5, SLC7A1 | GRIK1 517/4885GRIK2 310/4885SLC1A3 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.